Naloxone (Narcan)

Narcotic Antagonist

Effective in reversal and management of narcotic and synthetic narcotic overdoses.

Reverse effects of narcotics. Compete and displace narcotic molecules from opiate receptors.

• Onset: <2 min (IV) 2-10 min (IM/ET)
• Peak: <2min (IV) 2-10 min (IM/ET)
• Duration: 20-120 min
• Half-Life: 60-90 min

1.) Narcotic (i.e. morphine, dilaudid, fentanyl, demerol, paregoric, methadone, heroin, percodan, and tylox overdose.)

2.)Synthetic analgesic overdose including: Nabain, Stadol, Talwin, Darvon, and alcoholic coma.

History of hypersensitivity to drug

Withdrawal effects, short acting (augmenting 5 minutes), not used as a "Coma Cocktail"

Rare

1-2 mg

under 5 y/o give .1mg/kg. Older than 5 y/o give 2.0 mg.

Repeat as necessary

IV/IO/IN/ET

Prefilled syringes, vials and bristo-jets