Naloxone (Narcan)

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  1. Class
    Narcotic Antagonist
  2. Description
    Effective in reversal and management of narcotic and synthetic narcotic overdoses.
  3. Mechanism of Action
    Reverse effects of narcotics. Compete and displace narcotic molecules from opiate receptors.
  4. Onset of Action
    • Onset: <2 min (IV) 2-10 min (IM/ET)
    • Peak: <2min (IV) 2-10 min (IM/ET)
    • Duration: 20-120 min
    • Half-Life: 60-90 min
  5. Indications
    1.) Narcotic (i.e. morphine, dilaudid, fentanyl, demerol, paregoric, methadone, heroin, percodan, and tylox overdose.)

    2.)Synthetic analgesic overdose including: Nabain, Stadol, Talwin, Darvon, and alcoholic coma.
  6. Contraindications
    History of hypersensitivity to drug
  7. Precautions
    Withdrawal effects, short acting (augmenting 5 minutes), not used as a "Coma Cocktail"
  8. Side effects
  9. Adult Dose
    1-2 mg
  10. Pedi-Dose
    under 5 y/o give .1mg/kg. Older than 5 y/o give 2.0 mg.
  11. Max Dose
    Repeat as necessary
  12. Routes of Administration
  13. How Supplied
    Prefilled syringes, vials and bristo-jets
Card Set
Naloxone (Narcan)
Paramedic Drugs
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