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outer section (cortex) of each adrenal gland; secretes cortisol, aldosterone, and sex hormones
adrenal cortex
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inner section (medulla) of each adrenal gland; secretes epinephrine and norepinephrine
adrenal medulla
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lacated in the lower abdomen of a female; responsible for egg production and estrogen and progesterone secretion
ovaries
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located behind the stomach. Islet (alpha & beta) cells (islets of Langerhans) secrete hormones
pancreas
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four small glands on the posterior of the thyroid gland
parathyroid glands
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located at the base of the brain in the sella turcica; composed of an anterior lobe and a posterior lobe
pituitary gland (hypophysis)
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two glands enclosed in the scrotal sac of a male; responsible for sperm production and testosterone secretion
testes
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located in the neck on either side of the trachea; secretes thyroxine
thyroid gland
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secreted by the adrenal medulla; increases heart rate and blood pressure
adrenaline (epinephrine)
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secreted by the anterior lobe of the pituitary gland; stimulates the adrenal cortex
adrenocorticotropic hormone (ACTH)
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secreted by the adrenal cortex; increases salt (sodium) reabsorption
adosterone
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male homrone secreted by the testes and to a lesser extent by the adrenal cortex; testosterone is an example
androgen
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secreted by the posterior lobe of the pituitary gland; increases reabsorption of water by the kidney
antidiuretic hormone (ADH)
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secreted by the thyroid gland; decreases blood calcium levels
calcitonin
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secreted by the adrenal cortex; increases blood sugar; secreted in times of stress and has an anti-inflammatory effect
cortisol
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secreted by the adrenal medulla; increases heart rate and blood pressure and dilates airways (sympathomimetic); part of body's "fight or flight" reaction
epinephrine (adrenaline)
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estrogen (female hormone) secreted by the ovaries
estradiol
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female hormone secreted by the ovaries and to a lesser extent by the adrenal cortex; ex: estradiol and estrone
estrogen
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secreted by the anterior lobe of the pituitary gland; stimulates hormone secretion and egg production by the ovaries and sperm production by the testes
follicle-stimulating hormone (FSH)
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secreted by alpha islet cells of the pancrea; increases blood sugar by conversion of glycogen (starch) to glucose
glucagon
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secreted by the anterior lobe of the pituitary gland; stimulates growth of bones and soft tissue
growth hormone (GH); somatotropin
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secreted by beta islet cells; helps glucose to pass into cells and promotes conversion of glucose to glycogen
insulin
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secreted by the anterior lobe of the pituitary gland; stimulates ovulation in females nad testosterone secretion in males
luteinizing hormone (LH)
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secreted by the adrenal medulla; increases heart rate and blood pressure (sympathomimetic); parent compound from which another is derived (epinephrine)
norepinephrine
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secreted by the posterior lobe of the pituitary gland; stimulates contraction of the uterus during labor and childbirth
oxytocin (OT)
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secreted by the parathyroid glands; increases blood calcium
parathormone (PTH)
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secreted by the ovaries; prepares the uterus for pregnancy
progesterone
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secreted by the anterior lobe of the pituitary gland; promotes milk secretion
prolactin (PRL)
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secreted by the anterior lobe of the pituitary gland; growth hormone
somatotropin (STH)
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male hormone secreted by the testes
testosterone
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secreted by the anterior lobe of the pituitary gland; acts on the thyroid gland to promote its functioning
thyroid-stimulating hormone (TSH); thyrotropin
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secreted by the thyroid gland; increases metabolism in cells; also called tetraiodothyronine
thyroxine (T4)
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secreted by the thyroid gland; increase metabolism in cells
triiodothyronine (T3)
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secreted by the posterior lobe of the pituitary gland; antidiuretic hormone (ADH)
vasopressin
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hormones derived from an amino acid and secreted by the adrenal medulla
catecholamines
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hormones (steroids) produced by the adrenal cortex
corticosteroids
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mineral salt found in the blood and tissues and necessary for proper functioning of cells; include K, Na, Ca
electrolyte
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steroid hormone secreted by the adrenal cortex; regulates glucose, fat, and protein metabolism
glucocoticoid
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tendency of an organism to maintain a constant internal environment
homeostasis
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substance, secreted by an endocrine gland, that travels through the blood to a distant organ or gland where it influences the structure of function of that organ or gland
hormone
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region of the brain lying below the thalamus and above the pituitary gland; secretes releasing factors and hormones that affect the pituitary gland
hypothalamus
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steroid hormone secreted by the adrenal cortex to regulate mineral salts (electrolytes) and water balance in teh body
mineralocorticoid
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cullular or nuclear protein that binds to a hormone so that a response can be elicited
receptor
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cavity in the skull that contains the pituitary gland
sella turcica
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steroid (adrogens and estrogens) produced by the adrenal cortex to influence male and female sexual characteristics
sex hormones
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complex substance related to fats (derived from a sterol, such as cholesterol), and of which many hormones are made
steroid
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pertaining to mimicking or copying the effect of the sympathetic nervous system
sympathomimetic
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cells of an organ that affected or stimulated by specific hormones
target tissue
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adren/o, adrenal/o
adrenal gland
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gonad/o
sex glands (ovaries and testes)
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parathyroid/o
parathyroid gland
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pituitar/o
pituitary gland
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thyr/o, thyroid/o
thyroid gland
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cortic/o
cortex, outer region
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-agon
assemble, gather together
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-tropin
stimulating the function of (to turn or act on)
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hypo-
deficient; below, under; less than normal
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overactivity of the thyroid gland; thyrotoxicosis; Graves Disease
hyperthyroidism
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underactivity of the thyroid gland; myxedema=adult; cretinism=childhood
hypothyroidism
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cancer of the thyroid gland
thyroid carcinoma
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excessive production of parathormone
hyperparathyroidism
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deficient production of parathyroid hormone
hypoparathyroidism
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excessive secretion of adrenal androgens
adrenal virilism
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group of signs and symptoms produced by excess cortisol from the adrenal cortex
Cushing syndrome
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hypofunctioning of the adrenal cortex
Addison disease
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benign tumor of the adrenal medulla; tumor cells stain a dark or dusky color; produce excess epinephrine & norepinephrine
pheochromocytoma
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excess secretion of insulin causing hypoglycemia
hyperinsulinism
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lack of insulin secretion or resistance of insulin in promoting sugar, starch, and fat metabolism in cells
diabetes mellitus (DM)
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DM: autoimmune disease; early childhood onset; complete deficiency of insulin; ketoacidosis often occurs
Type 1 diabetes
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DM: insulin resistance; older onset; obesity; metabolic syndrome
Type 2 diabetes
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hypersecretion of growth hormone from the anterior pituitary after puberty, leading to enlargement of extremities
acromegaly
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hypersecretion of growth hormone from the anterior pituitary before puberty, leading to abnormal overgrowth of body tissues
gigantism
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congenital hyposecretion of growth hormone; hypopituitary dwarfism
dwarfism
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deficiency of all pituitary hormones
panhypopituitarism
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excessive secretion of antidiuretic hormone
syndrome of inappropriate ADH (SIADH)
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insufficient secretion of antidiuretic hormone (vasopressin)
diabetes insipidus (DI)
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also known as fasting blood sugar test; measures circulating glucose level in a patient who has fasted at least 8 hours; can diagnose diabetes and pre-diabetes
fasting plasma glucose (FPG)
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measurement of hormones, electrolytes, glucose, and other substances in serum (blood) and urine as indicators of endocrine function
serum and urine tests
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measurement of T3, T4, and TSH in the bloodstream
thyroid function tests
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measurement of eyeball protrusion (as in Graves disease) with an exophthalmometer
exophthalmometry
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x-ray imaging of endocrine glands in cross section and other views, to assess size and infiltration by tumor
CT scan
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magnetic waves produce images of the hypothalamus and pituitary gland to locate abnormalities
MRI
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radioactive iodine is administered orally, and its uptake by the thyroid gland is imaged to assess thyroid function
radioactive iodine uptake (RAIU) scan
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scanner detects radioactivity and visualizes the thyroid gland after intravenous administration of a radioactive (technetium) compound
thyroid scan
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sound waves show images of endocrine organs
ultrasound examination
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