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Antianginal and Anti-hypertension
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Nitroglycerine
Causes smooth muscle dilation
Taken under tongue to avoid 1st pass effect
Steps for smooth muscle contraction
Nitrates>Nitrites>Nitric oxide>GMP>Myosin light chain
All are increasesd
Treatment Hypertension
ACE inhibitors
Inhibit renin and angiotensin II
Increase sypathetic tone by using B blockers
Diuretics
Thiazide
Direct arteriole effect, removes Na and H2O in order to lower blood volume
Diruetic
Drug of choice
Bradykinin
Causes dry cough
Broken down by ACE
Author
Kate718
ID
98985
Card Set
Antianginal and Anti-hypertension
Description
Chapter 19
Updated
2011-08-30T05:44:26Z
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