Antianginal and Anti-hypertension

Nitroglycerine
- Causes smooth muscle dilation
- Taken under tongue to avoid 1st pass effect
Steps for smooth muscle contraction
- Nitrates>Nitrites>Nitric oxide>GMP>Myosin light chain
- All are increasesd
Treatment Hypertension
- ACE inhibitors
- Inhibit renin and angiotensin II
- Increase sypathetic tone by using B blockers
- Diuretics
Thiazide
- Direct arteriole effect, removes Na and H2O in order to lower blood volume
- Diruetic
- Drug of choice
Bradykinin
- Causes dry cough
- Broken down by ACE

Author

Kate718

98985

Card Set

Antianginal and Anti-hypertension

Description

Chapter 19

Updated

2011-08-30T05:44:26Z

Show Answers