HF, Angina, Dysrhythmias

  1. The principal drugs employed for treatment of heart failure are
    • Angiotensin-converting enzyme inhibitors (ACE), diuretics,
    • beta blockers,
    • digoxin.
  2. Remodeling is a process in which the ventricles
    dilate, hypertrophy and become more spherical.
  3. The principal adverse effects of the angiotensin-converting enzyme (ACE) inhibitors are
    hypotension, hyperkalemia and cough
  4. The oldest and most frequently prescribed inotropic drugs are the
    cardiac glycosides.
  5. Spironolactone has two adverse effects of concern. They are
    gynecomastia and hyperkalemia.
  6. A drug that provides a positive inotropic effect on the heart causes
    increased force of contraction, thereby increasing cardiac output.
  7. Beneficial effects of digoxin in the treatment of heart failure include
    increased cardiac output, consequences of increased cardiac output, decreased sympathetic tone, increased urine output and decreased renin release.
  8. The most common cause of dysrhythmias in patients receiving digoxin is
    hypokalemia secondary to the use of diuretics.
  9. The principal noncardiac toxicities of digoxin concern the
    Gastrointestinal system and the central nervous system.
  10. The therapeutic plasma level of digoxin is
    0.5 to 0.8 ng/ml.
  11. Is the use of antidysrhythmic drugs increasing or decreasing?
  12. The term arrhythmia denotes a(n)______of
    cardiac rhythm, whereas dysrhythmia denotes a(n)_______rhythm
    • Absence
    • abnormal
  13. Phase 3 repolarization can be delayed by drugs that block
    potassium channels
  14. The treatment of choice for sustained ventricular tachycardia is
  15. The most common adverse effect of quinidine is
  16. Lidocaine is the treatment of choice for
    short term therapy of ventricular dysrhythmias__.
  17. The major adverse effect of bretylium is
    Profound Hypotension
  18. What is the current drug of choice for terminating paroxysmal supraventricular tachycardia (SVT)
  19. What are the four families of antianginal agents?
    • organic nitrates,
    • calcium channel blockers,
    • beta blockers
    • ranolazine.
  20. The underlying cause of exertional angina is
    coronary artery disease
  21. Beta blockers are effective in which type of angina?
    Stable Angina
  22. Eptifibatide (Integrilin) and tirofiban (Aggrastat) are used as which type of therapy?
  23. How many hours a day should a patient receiving nitroglycerin therapy be drug-free of this medication? __
    8 hours
  24. How is nitroglycerin administered via the intravenous (IV) route?
    Administration should be performed using a glass IV bottle and the administration set provided by the manufacturer
  25. Adverse effects of beta blockers include
    bradycardia, decreased AV conduction, reduced contractility, insomnia, depression, bizarre dreams and sexual dysfunction.
  26. If an asthmatic individual absolutely must use a beta blocker, which one should be administered?
    Cardiac selective, metoprolol.
  27. The major adverse effect of the calcium channel blockers is
    reflex tachycardia
  28. Cardiac oxygen demand is determined by
    heart rate, contractility, preload and afterload.
Card Set
HF, Angina, Dysrhythmias