Cholera develops when the bacterial toxin ____
A) inhibits the enzyme that normally breaks down cAMP
B) prevents G-protein inactivation, which leads to the continuous production of cAMP
C) inhibits adenylyl cyclase, preventing cell from producing cAMP
D) blocks the receptor site for cAMP
E) phosphorylates the cAMP, producing ADP
B) prevents G-protein inactivation, which leads to the continuous production of cAMP
The activated G protein continuously stimulates adenylyl cyclase to make cAMP, which causes the intestinal cells to secrete large amounts of water and salts into the intestines