Pharm Week 9

  1. -olol
    • beta blockers
    • Beta 1: reduce calcium entry, reduce conduction velocity, automaticity, and recovery time. Decreases heart rate and contractility which decreases O2 demand.
    • Beta 2: bronchoconstiction
  2. -sartan
    • Angiotensin receptor II blockers (ARB's)
    • Prevent the release of aldosterone (sodium retaining hormone)
    • act on the renin-angiotensin-aldosterone system
    • block angiotension II from the AT1 receptors
    • cause vaso dilation and decrease periheral resistance
    • do not cause cough
  3. -pril
    • Angiotensin-Converting Enzyme inhibitors (ACE)
    • inhibit formation of angiotensin II (vasoconstrictor) and blocks release of aldosterone
    • promotes sodium & water excretion, potassium retention
    • cause little change in cardiac output or heart rate, but lower peripheral resistance
    • treat hypertension, some heart failure
    • cause caugh
  4. -ipine
    • calcium channel blockers
    • Block calcium in vascular smooth muscle =vasodilation
    • Relaxation of coronary arteries which decreases vasospasms and increases O2 supply.
    • Dilation of arterioles which decreases afterload and decreases O2 demand.
  5. -statin
    • anti-cholesterol
    • inhibit the enzyme HMG CoA reductase
    • inhibits the synthesis of cholesterol in the liver to decrease the concentration of cholesterol, decreases LDL, slightly increases HDL
    • may see results with in two weeks, but are a lifetime drug
  6. -vir
    • antivirals
    • used to prevent or delay the spread of a viral infection
    • inhibit viral replication by interfering with viral nucleic acid synthesis in the cell
Card Set
Pharm Week 9
generic name endings