-
Fracastoro
diseases caused by spores
-
Va leeuwenhoek
1st described microbes, invented microscope
-
-
lister
antiseptic in surgery
-
pasteur
- germ theory
- pasteurization
- disproved spontaneous generation
-
-
griffith
bacteria are capable of transfering genetic information
-
avery, mccarty, macleod
transforming substance is DNA
-
watson and crick
dna structure
-
john cairns
chromosome is circular
-
-
-
-
coccobacillus
rod shaped with round ends
-
spirochete
spiral shaped with unique motility
-
pleomorphic
vary in shape
-
gram positive
- thick peptidoglycan
- stain purple
- contain teichoic acids (give it negative charge)
-
gram negative
- thin peptidoglycan
- outer membrane surrounds peptido
- lipopolysaccharide
- stain pink
-
acid fast cell
- cell wall with high lipid content (dont take up stain)
- require unique dyes and heat
- mycobacterium - all are acid fast
-
cells with no cell wall
have high sterol content for rigidity
-
mesosome
invaginations of the cytoplasmic membrane that forms vesicles
-
periplasmic space
space b/t inner and outer membranes in gram negative
-
nucleoid
region of bacterial cell containing dna
-
plasmid
extrachromosomal dna, autonomous replication
-
ribosomes
organelles composed of rRNA and protein
-
storage granules
- accumulations of high molecular weight polymers
- also called inclusion bodies, granular inclusions
-
-
pili (fimbriae)
- adherence factors
- can be v. factor
-
capsule = glycocalyx
- protective walls
- v. factor - impedes phagocytosis
-
endospore
- 2 gram + genera - bacillus, clostridium
- protective not reproductive
- resist heat, drying, disinfectants
-
earliest classification system
- linnaeus - 2 kingdoms
- then 5, then 6
-
3 domain system
- comparison of DNA sequence
- bacteria
- archaea
- eukarya
-
bacterial nomenclature
- kingdom
- phylum
- class
- order
- family
- genus
- species
- strain
-
bacterial identification
- based on:
- morphological characteristics
- biochemical testing
- molecular taxonomy
- PCR
- Immunological tests
-
biochemical testing
test for utiization of different substrates
-
immunological tests
- analyze blood serum for specific antibodies
- the serotype indicates the possesion of antigens
-
|
|
