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nerve cells; the basic unit of nerves
neurons
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terminal zone of nerve axon, known as junctions, also contain numerous organelles
synapses
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the spaces between adjacent Schwann cells where nerve membranes can be exposed to local anesthetic drugs in myelinated nerves
nodes of ranvier
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the inner layer of the perineurium
perilemma
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the potential across a nerve; whenever it is not 0 mV
polarized
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when the potential across the membrane is 0 mV
depolarized
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a state following a nerve impulse generation in which a subsequent impulse generation is either temporarily impossible or more difficult
refractory state
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the period in which a partial attainment of the resting state has occurred and during which a larger stimulus is required in order to achieve a successful firing along previously fired segments of nerve membranes
relative refractory state
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the state in which a nerve is receiving little or no stimulation
resting state
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the process whereby impulses are more rapidly conducted along myelinated nerves due to a decrease in the length of membrane along which impulses must be generated in order to reach their destinations
saltatory conduction
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connective tissue cells that protect neurons in the peripheral nervous system
schwann cells
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Schwann cells, described as enclosing neurons
schwann cell sheaths
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nerves that relay information to the CNS regarding tissue injury and stimulation
sensory nerves
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the initial depolarization or electrical activity along a nerve membrane during which there is insufficient depolarization to generate a nerve impulse
slow depolarization
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active pumps that enhance the movement of sodium ions both into and out of sodium channels
sodium ion pumps
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the areas in ion channels of nerve membranes in which local anesthetic molecules are bound
specific protein receptor site
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tree-like zones of neurons where impulses are transmitted to other nerves or nuclei of the CNS
terminal aborization
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the period during which the generation of new impulses along previously fired sections of nerve membranes is physiologically impossible
absolute refractory period
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a synonym for impulse, which refers to the electronic signal generated and conducted to the CNS and from the CNS to effector organs, cells, and tissues in response to stimulation
action potential
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the processes or fibers of individual nerve cells that transmit signals to and from the central nervous system
axon
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bilayered, phospholipid membranes of neurons, also known as neurolemmas
axolemmas
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the cytoplasm or intracellular environment of a nerve cell
axoplasm
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the part of a neuron that provides metabolic support and, in the case of motor neurons, also conducts impulses
cell body
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a term referring to the relative amounts of substances on differing sides of membranes (in local anesthesia, neural membranes)
concentration gradient
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the fasciculi in the central region of the mantle bundles
core bundles
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a zone of a sensory nerve where stimulation occurs
dendritic zone
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the network of nerves surrounding teeth that innervate the pulp and their supporting structures
dental neural plexus
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to transform an area of nerve membrane from an excitable to a less excitable or nonexcitable state
depolarize
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greater volumes of solution are required to accomplish impulse extinction
durable blockade
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the difference in electrical charge across a membrane
electrical potential
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the anatomic structure that separates individual nerve fibers and insulates their electrical activity
endoneurium
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the outer covering of the epineurium
epineural sheath
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the loose connective tissue layer that surrounds the fasciculi, their associated supporting connective tissue including blood vessels and lymphatics, and the perineuria
epineurium
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the outer environment of nerves beyond their membranes and associated Schwann cells
extracellular
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bundle of nerve fibers
fasciculi
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the point at which a sufficient change in electrical potential has occurred to generate a nerve impulse
firing threshold
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a group of nerve cell bodies outside the CNS
ganglia
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signals generated and conducted along nerve membranes that provide the CNS with awareness of tissue stimulation or damage or that initiate reactions from effector organs and tissues in response to the stimulation or damage
impulses
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the interruption of impulse propagation along particular areas of nerve membranes (local anesthesia induces impulse extinction)
impulse extinction
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the environment within cell membranes, in this case, nerve cell membranes
intracellular
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pathways within nerve membranes through which charged atoms can pass
ion channels
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lipid or fat loving
lipophilic
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any drug that renders nerve tissues insensitive to stimulation by preventing the generation and conduction of nerve impulses
local anesthesia
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nerves that transmit impulses from the CNS to effector cells, tissues, and organs
motor nerves
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refers to nerves that are enclosed by multiple layers of Schwann cells
myelinated
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axons and their associated Schwann cells
nerve fibers
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the outer membrane of a neuron, also known as an axolemma
neurolemma
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