Confirmatory factor analysis of schizophrenia symptoms reveal what?
- Lenzenweger and Dworkin 1996
- 3 factors: negative symptoms, reality distortion, disorganization with fourth possible premorbid social impairment
factor analytic studies of schizotypic signs and symptoms reveal what?
- solutions that are broadly consistent with those of schizophrenia:
- Raine (1991): 3 factor model consisting of cognitive/perceptual, disorganization, interpersonal
- So, phenotypically, schizotypes not only seem like attenuated sz, but the latent organization appears similar.
How can you assess schizotypic psychopathology?
- 1. signs and symptoms
- 2. devince on reliable laboratory measures
- 3. first degree biological relative diagnosed with schizophrenia
- Lenzenweger, 1998
Meehl's theory of schizotypy
- influenced by Rado (1953, 1960)
- etiologic framework that encompasses genetic factors, social learning influences and clinical symptomatology.
According to Meehl 1990, schizophrenia occurs because of:
- 1) a schizotaxic brain which is characterized by hypokrisia resulting from the presence of the schizogene
- 2) environmentally mediated social learning experiences
- 3) Polygenic potentiators (other genetic factors separate from the schizogene that, given the presence of the schizogene, raise the probability of clinical decompensation)--example, introversion, anxiety sensitivity, hypohedonia.