Pharm

  1. atorvastatin- Lipitor
    (MOA, Admin alert, Preg, SE, Inter.)
    • MOA: HMG-CoA reductast inhibitor: blocks production ofcholesterol
    • Admin: taken w/ food, may be taken anytime of day
    • Pregnancy X
    • SE: Muscle breakdown, GI upset, myopathies, liver damage
    • Interactions: Grapefruit juice
  2. choestyramine- Questran
    (MOA, Admin, SE)
    • MOA: binds bile acids decreasing chlesterol levels by 20%
    • Admin: take before meals, other meds 1 hr befor or 4 hrs after
    • SE: Severe GI upset, Vit. depletion, decrease absorb. of other meds
  3. gemfibrozil- Lobid
    (MOA, Admin, SE, Inter.)
    • MOA: Decrease VLDL by 50%/ increase HLDs
    • Admin: take w/food to decrease GI upset
    • SE: Cramping,diarrhea, gallstones or liver dysfunction
    • Inter: increase levels of coumadin, use w/ statins may potentiate myopathies
  4. hydrochlorothiazide- HydroDiuril
    (Use, MOA, SE, Inter.)
    • Use: Hypertension-Diuretic
    • MOA: act on renal tubules to decrease absorption of Na
    • SE: K, Na depletion, Hyperglcemia
    • Interaction: NSAID decrease action
  5. Calcium Channel Blockers- amilodipine
    (MOA, SE, Inter.)
    • MOA: selectively blocks calcium channels in myocardium and
    • vasculature
    • SE: headaches, dizziness, flushing, reflex tachycardia
    • Inter: Grapefruit juice increase absorb, alcohol potentiates vasodilation effects
  6. lisinopril-Prinivil
    (MOA,SE)
    • MOA: RAS
    • SE: bradykinin buildup becuse of blockage of AI to AII
  7. doxazosin-Cardura
    (Use, MOA, SE)
    • Use: Alpha I adrenergic blocker for hypertentsion
    • MOA: dilates arteries and veins causing a decrease in BP
    • SE: first doese phenomenon, orthostatic hypotension, shrinks prostate
  8. hydralazine- Apresoline
    (Use, MOA, SE)
    • Use: direct vasodilator
    • MOA: relaxation of smooth arteriolar smooth muscles
    • SE: severe reflext tachycardia, fluid retention
  9. Inotrope
    Squeeze
  10. chronotrope
    the heart rate
  11. furosemide-Lasix
    (Use, MOA, SE)
    • Use: Loop Diuretics
    • MOA: pulling fluid
    • SE: fluid overload, hypokalemia
  12. metoprolol-Lopressor
    (Use, MOA, SE, NC)
    • Use: Beta-adrenergic Blockers
    • MOA: negative inotrope, negative chronotrope- slows heart
    • SE:anxiety, heart failure
    • NC: Low BP, HR, mood, impotence
  13. digoxin-Lanoxin
    (Use, MOA, SE, NC)
    • Use: Cardiac Glycoside
    • MOA: positive isotrope, negative chronotrope
    • SE: low HR
    • NC: narrow therapeutic window: hold if HR <60
  14. milrinone-Primacor
    (Use, MOA, SE, NC)
    • Use: phosphodiesterase inhibitors
    • MOA: positive inotrope
    • SE: hypertension then hypotension
    • NC: continuous monitoring
  15. Nitroglycerine
    • Inactiviated by light, heat, and air
    • Glass bottle and special tubing
    • Covered bottle and tubing against light
    • Headache common SE
    • Sublingual peak levels in 4 minutes
  16. procainamide-Pronestyl
    (Use, MOA, SE, NC)
    • Use: sodium channel blockers
    • MOA: reduces ventricular arythmias
    • SE: cause Lupis
    • NC: cardiac monitoring
  17. amiodarone-Cardarone
    (Use, MOA, SE)
    • Use: Potassium Channel Blockers
    • MOA: Atrial fibrilation/ ventricular arrhythmias
    • SE: pulmonary fibrosis, blue hue to skin
  18. Low molecular weight heparins
    • More stable than IV heparin
    • Can be Sub Q
    • Drug of choice for DVT
  19. Heparin
    (MOA, Admin, measured, antidote)
    • MOA: prolongs bleeding times
    • Admin: IV or Sub Q
    • Measured in units
    • Antidote: protomine sulfate neutralizes
  20. aPtt
    • activated partial thromboplastin time
    • how long it takes someone to stop bleeding
  21. warfarin- Coumadin
    (MOA, SE, NC)
    • MOA: effecting vit. K dependent clotting factors (Sink)
    • SE: diet high in vit K reduce effects, minor bleeding
    • NC: monitor signs of bleeding, monitor PT(prothrombin time) which is reported in INR
  22. clopidogrel bisulfate-Plavix
    (Use, MOA, Indication, SE)
    • Use: antiplatelet agents
    • MOA: ADP receptor blockers alter platelet membrane
    • Indication: Post thromboembolic event (MI, CVA)
    • SE: few and mild, headache, dizziness, rash
    • Contraindication: active bleeding-don't give w/ NSAIDs
  23. reteplase
    (Use, MOA, Contra)
    • Use: thrombolytics
    • MOA: dissolves clots
    • Contra: Any recent trauma, active bleeding
    • Must be given in 6 hrs of MI and 3 hrs for CVA
  24. Erythropoietin
    (Use, MOA, SE)
    • Use: Hematopoieti Growth Factors
    • MOA: promote formation of RBC
    • SE: Increase risk of clotting
  25. ferrous sulfate
    (Use, MOA, SE, NC)
    • Use: Iron deficiency anemia
    • MOA: replenish iron stores
    • SE: constipation
    • NC: take with OJ, toxic to children
  26. dopamine
    (Use, MOA)
    • Use: inotropic agent
    • MOA: stronger contraction of heart
  27. epinephrine
    (Use, MOA, SE)
    • Use: anaphylaxis
    • MOA: vasoconstriction and opens bronchial tree
    • SE: tachycardia
  28. spironolactone
    (MOA, Indic.)
    • MOA: inhibit the action of aldosterone, K sparing diuretic
    • Indic: adjunt therapy for hypertension, adjunct therapy for hirsutism
  29. dextran
    (MOA, Uses, concerns)
    • MOA: blood volume expander
    • Use: hypovolemic shock, reduction of platelet adhesiveness
    • concerns: fluid overload, reactions, prolonged bleeding
  30. Potassium Chloride
    (Use, Alerts)
    • Use: treatment of hypokalemia
    • Alerts: vital signs, IV must be given slowly, carefully monitor IV site for infiltrations, oral prep can cause GI upset, monitor electrolytes as ordered
Author
brinnjo
ID
9619
Card Set
Pharm
Description
Pharm
Updated