-
atorvastatin- Lipitor
(MOA, Admin alert, Preg, SE, Inter.)
- MOA: HMG-CoA reductast inhibitor: blocks production of cholesterol
- Admin: taken w/ food, may be taken anytime of day
- Pregnancy X
- SE: Muscle breakdown, GI upset, myopathies, liver damage
- Interactions: Grapefruit juice
-
choestyramine- Questran
(MOA, Admin, SE)
- MOA: binds bile acids decreasing chlesterol levels by 20%
- Admin: take before meals, other meds 1 hr befor or 4 hrs after
- SE: Severe GI upset, Vit. depletion, decrease absorb. of other meds
-
gemfibrozil- Lobid
(MOA, Admin, SE, Inter.)
- MOA: Decrease VLDL by 50%/ increase HLDs
- Admin: take w/food to decrease GI upset
- SE: Cramping,diarrhea, gallstones or liver dysfunction
- Inter: increase levels of coumadin, use w/ statins may potentiate myopathies
-
hydrochlorothiazide- HydroDiuril
(Use, MOA, SE, Inter.)
- Use: Hypertension-Diuretic
- MOA: act on renal tubules to decrease absorption of Na
- SE: K, Na depletion, Hyperglcemia
- Interaction: NSAID decrease action
-
Calcium Channel Blockers- Nifedipine
(MOA, SE, Inter.)
- MOA: selectively blocks calcium channels in myocardium and vasculature
- SE: headaches, dizziness, flushing, reflex tachycardia
- Inter: Grapefruit juice increase absorb, alcohol potentiates vasodilation effects
-
lisinopril-Prinivil
(MOA,SE)
-
doxazosin-Cardura
(Use, MOA, SE)
- Use: Alpha I adrenergic blocker for hypertentsion
- MOA: dilates arteries and veins causing a decrease in BP
- SE: first doese phenomenon, orthostatic hypotension, shrinks prostate
-
hydralazine- Apresoline
(Use, MOA, SE)
- Use: direct vasodilator
- MOA: relaxation of smooth arteriolar smooth muscles
- SE: severe reflext tachycardia, fluid retention
-
-
chronotrope
the heart rate
-
furosemide-Lasix
(Use, MOA, SE, NC)
- Use: Loop Diuretics
- MOA:
- SE:
- NC:
-
metoprolol-Lopressor
(Use, MOA, SE, NC)
- Use: Beta-adrenergic Blockers
- MOA:
- SE:
- NC: Low BP, HR, mood, impotence
-
digoxin-Lanoxin
(Use, MOA, SE, NC)
- Use: Cardiac Glycoside
- MOA: positive isotrope, negative chronotrope
- SE:
- NC: narrow therapeutic window: hold if HR <60
-
milrinone-Primacor
(Use, MOA, SE, NC)
- Use: phosphodiesterase inhibitors
- MOA: positive inotrope
- SE: hypertension then hypotension
- NC: continuous monitoring
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