-
Isoproterenol
- Beta 2 agonist, relaxes bronchiolar smooth muscle
- Activation of beta 1 receptors causes tachycardia
-
Albuterol
- Specific beta 2 agonist
- Use for acute asthma attacks
-
Salmeterol
Long acting beta 2 agonist, use for prophylaxis against asthma attacks
-
Theophylline
- A methylxanthine, inhibits phosphodiesterases which increases cAMP concentration
- Use for asthma
- Cardiotoxic
- Blocks action of adenosine
-
Ipratropium
- A muscarinic antagonist, causes competitive blockade of muscarinic receptors, which prevents bronchoconstriction
- Use for asthma and COPD
-
Cromolyn
- Prevents release of mast cell mediators
- Use for prophylaxis of asthma
-
Beclomethasone, prednisone
- Steroids. Inhibit cytokine synthesis and NFkappa-B, which induces production of inflammatory agents
- First line treatment for chronic asthma
-
Flunisolide
Aerosolized steroids, use for asthma
-
Zileuton
- Inhibits the lipoxegenase pathway, blocks leukotriene synthesis
- Use for asthma
-
Zafirlukast, montelukast
- Block leukotriene receptors
- Use for aspirin-induced asthma
-
N-acetylcysteine
- Sulfhydryl group donor, breaks up mucus plugs in CF patients
- Also used for acetaminophen toxicity
-
Bosentan
Competetive antagonist of endothelin receptors, used to treat pulmonary hypertension
|
|
