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what is Hibernating myocardium?
reduced perfusion and contraction resulting in chronic LV dysfunction. this is reverseable with restoration of myocardial perfusion.
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what is stunned myocardium?
- abnormal contraction despite normal coronary blood flow.
- May persist for days/weeks following angioplasty or thrombolytic therapy, making it difficult to assess the therapy
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Radionuclides Used for Cardiac PET?
half life? apprx dose? production?
- 18F-FDG, 110min, 10mCi, cyclotron
- Rubidium-82, 75sec, 50mCi, generator
- N13, 10min, cyclotron, 20mCi
- O15, 122sec, cyclotron, 10mCi
- C11, 20 min, cyclotron
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Cardiac PET agents for perfusion?
N13 and Rb-82
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Cardiac PET agents for viability?
F-18 fluorodeoxyglucose
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