-
Pt presents with:
cough, rash, proteinuria, angioedema, taste changes, teratogenic effects
ACEIs
-
Pt presents with:
ataxia, livedo reticularis (lace-like purplish discoloration of the lower extremities)
Amantadine
-
Pt presents acutely with:
AV block, hypotension, bradycardia
Amiodarone
-
Pt presents with chronic complaints of:
pulmonary fibrosis, peripheral deposition leading to bluish discoloration, arrhythmias, hypo-hyperthyroidism, corneal deposition
Amiodarone
-
Pt presents with:
Fevers/rigors, nephrotoxicity, bone marrow suppression, anemia
Amphotericin
-
HIV patient presents with
Thrombocytopenia, megaloblastic anemia
Zidovudine (AZT)
-
Hypercholesterolemic pt presents with:
GI upset, malabsorption of vitamins and medications
- Bile acid resins:
- Cholestyramine
- Colestipol
- Colesevelam
-
Pt with arrhythmias presents with:
peripherial edema, flushing, constipation, cardiac depression
- CCBs:
- Dihydrophyridines - nifedipine, felodipine, amlodipine
Nondihydropyridines - diltiazem, verapamil
-
Bipolar patient presents with:
agranulocytosis, aplastic anemia, liver toxicity
drug can also induce P-450
carbamazepine
-
Antibiotic that presents with:
gray baby syndrome, aplastic anemia, and hemolysis in G6PD deficient patients
Chloramphenicol
-
Chemotherapeutic agent causes:
nephrotoxicity, acoustic nerve damage
cisplatin
-
Pt with hx of HTN presents with:
dry mouth; severe rebound headache and HTN
clonidine
-
Atypical antipsychotic known for:
agranulocytosis
Clozapine
-
Immunosuppression agent that causes pts to have:
mania, hyperglycemia, bone mineral loss, thinning of skin, easy bruising, myopathy, cataracts (chronic)
corticosteroids
-
Chemotherapeutic agent that causes:
myelosuppression, hemorrhagic cystitis
cyclophosphamide
-
Antiarrhythmic that causes:
GI disturbances, yellow visual changes, arrhythmias (junctional tachycardia or SVT)
digoxin
-
Chemotherapeutic agent known for:
cardiotoxicity (cardiomyopathy)
doxorubicin
-
Used to treat methanol or ethylene glycol toxicity causes:
renal dysfunction, CNS depression
Ethyl alcohol
-
ATBX that causes:
cartilage damage in children; achilles tendon rupture in adults
- Fluoroquinolones:
- ciprofloxacin
- levofloxacin
- ofloxacin
-
HTN pt presents with:
ototoxicity, hypokalemia, nephritis, gout
Furosemide
-
Pt with hypercholesteremia presents with:
myositis, reversible increase in LFTs, cholelithiasis, GI upset
gemfibrozil
-
Anesthetized pt with:
malignant hyperthermia, hepatotoxicity
halothane
-
HTN pt with:
Hypokalemia
Hyponatremia
Hyperuricemia
Hyperglycemia
Hypercalcemia
HCTZ
-
Hyperlipidemic pt presents with:
increase LFTs, myositis, warfarin potentiation
- HMG-CoA reductase inhibitors
- simvastatin
- atorvastatin
- lovastatin
- pravastatin
- rosuvastatin
-
SLE patient with malaria presents with:
retinopathy
hydroxycholoroquine
-
Patient with malaria presents with:
peripheral neuropathy, hepatotoxicity, inhibition of P-450, seizures with overdoes, hemolysis in G6PD deficiency
INH
prophylaxis w/ pyridoxine (vit B6)
-
Depressed patient presents with:
hypertensive tyramine reaction, serotonin syndrome with meperidine
- MAOIs:
- phenelzine
- tranylcypromine
- selegiline
-
Other than metabolic acidosis, overdose of this can cause:
blindness
methanol
-
Immunosuppressive agent that causes:
hepatic fibrosis, pneumonitis, anemia
methotrexate
-
Alpha2 agonist used for HTn that can cause:
+ Coombs' test, drug-induced SLE, blood dyscrasias,
Methyldopa
-
Pt with hx of STD presents with:
disulfiram reaction, vestibular dysfunction, metallic taste
metronidazole
-
Hyperlipidemic pt presents with
Skin flushing, paresthesias, pruritis, GI upset, and increased LFTs
Niacin
-
Pt with acute MI develops:
hypotension, tachycardia, headache, tolerance
Nitroglycerin
-
Used in patients with RA, Wilson's disease, arsenic poisoning, lead toxicity, primary biliary cirrhosis causes
drug-induced SLE
penicillamine
-
HTN agent with
first dose hypotension
prazosin
-
Antiarrhythmic agent used for ventricular arrhythmias and SVTs presents with
drug-induced SLE
procainamide
-
Pt with Grave's disease presents with
agranulocytosis, aplastic anemia
propylthiouracil
-
Antiarrhythmic and malarial agent used to treat atrial flutter, afib and ventricular arrhythmias that presents with;
headache, tinnitus, thrombocytopenia, torsades de pointes, induces P-450, increase risk of digoxin toxicity, and drug induced SLE
Quinidine
-
HTN patient presents with
depression
reserpine
-
Epileptic pt with:
nystagmus, diplopia, ataxia, arrhytmia, gingival hyperplasia, hirsutism, teratogenic effects
Phenytoin
-
Pt with hx of stroke presents with:
fever, hyperventilation with respiratory alkalosis and metabolic acidosis, dehydration, diaphoresis, hemorrhagic gastritis
-
Pt with hx of depression presents with:
anxiety, sexual dysfunction, serotonin syndrome if taken with MAOIs
- SSRIs:
- fluoxetine,
- sertraline
- paroxetine
- citalopram
- fluvoxamine
-
Pt with neuromusclar blockade presents with:
malignant hyperthermia, hyperkalemia
succinylcholine
-
Pt with hx of depression:
sedation, coma, anticholinergic effects, seizures and arrhythmias
- TCAs:
- nortriptyline
- desipramine
- amitriptyline
- imipramine
-
ATBX that causes:
tooth discoloration, photosensitivity, Fanconi's syndrome, GI distress
- Tetracyclines:
- demeclocycline
- doxycycline
- minocycline
- tetracycline
-
ATBX that causes:
megaloblastic anemia, leukopenia, granulocytopenia
Trimethoprim
-
Bipolar or psychotic patient with:
neural tube defects, and fata hepatotoxicity
Valproic acid
-
ATBX that causes:
nephrotoxicity, ototoxicity, and "red man syndrome"
Vancomycin
-
Chemotherapeutic agent that causes:
severe myelosuppression
Vinblastine
-
Chemotherapeutic agent that causes:
peripheral neuropathy, paralytic ileus
vincristine
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