What are the 3 differences between drug actions on CNS and ANS
1. CNS includes inhibitory neurotransmitters
2. Blood brain Barrier is involved
3. Hyperpolarization
What are the 2 neurotransmitter classifications in the CNS
1. Excitatory
2. Inhibitory
Name the 5 Excitatory neurotransmitters in the CNS?
1. Epinephrine
2. Noraepinephrine
3. Achetylcholine
4. Glutamate
5. 5-HT
Name the 2 inhibitory Neurotransmittersin the CNS?
1. DA
2. Gaba
What is a Seizure?
A small population of neurons that goes through this rhythmic synchronous firing that causes a transient alteration in behaviour. Think of arrhythia of the brain.
What is a convulsion?
the jerkings and the spasms. (Commonly confused with seizures)
What causes seizures?
1. Hyperexcitability of neurons
2. Mechanical
3. Sudden drug withdrawal
4. Toxins
5. Heredity
6. Idiopathic
What are Partial seizures?
siezures that happen only at the location where the bad nuerons exist. This is where most seizures happen
What are generalized seizures?
When bad neurons recruit other neurons during a seizure and convulsions usually proceed.
What are the signs of partial seizures?
1. No loss of consciousness, just tingling or numbing