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anaphase
Mitotic phase during which daughter chromosomes move toward the poles of the spindle.
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angiogenesis
Formation of new blood vessels; one mechanism by which cancer spreads.
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apoptosis
Programmed cell death involving a cascade of specific cellular events leading to death and destruction of the cell.
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aster
Short, radiating fibers produced by the centrosomes in animal cells.
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benign tumor
Tumor that does not invade adjacent tissue and stays at the site or origin.
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cancer
Malignant tumor whose nondifferentiated cells exhibit loss of contact inhibition, uncontrolled growth, and the ability to invade tissue and metastasize.
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carcinogenesis
Development of cancer
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cell cycle
Repeating sequence of events in eukaryotes that involves cell growth and nuclear division; consists of the stages G1, S, G2, and M.
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cell plate
Structure across a dividing plant cell that signals the location of new plasma membranes and cell walls.
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centromere
Constricted region on a chromosome joining two sister chromatids.
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centrosome
Central microtubule organizing center of cells. In animal cells, it contains two centrioles.
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check point
In the cell cycle, one of several points where the cell cycle can stop or continue on, depending on the internal signal it receives; ensures that each step of the cell cycle is completed before the next one begins.
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chromatid
A single DNA strand of a chromosome. Chromosomes may consist of a pair of sister chromatids.
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chromatin
Network of fibrils consisting of DNA and associated proteins observed within a nucleus that is not dividing.
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chromosome
Structure consisting of DNA complexed with proteins that transmits genetic information from the previous generation of cells and organisms to the next generation.
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contact inhibition
In cell culture, the point where cells stop dividing when they become a one-cell thick sheet.
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cyclin
Protein that cycles in quantity as the cell cycle progresses; combines with and activates the kinases that function to promote the events of the cycle.
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cytokinesis
Division of the cytoplasm following mitosis and meiosis.
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DNA replication
Synthesis of a new DNA double helix prior to mitosis or meiosis in eukaryotic cells and during prokaryotic fission in prokaryotic cells.
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histone
Protein molecule responsible for packing chromatin.
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interphase
Stages of the cell cycle (G1, S, G2) during which growth and DNA synthesis occur when the nucleus is not actively dividing.
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kinase
Enzyme that activates another enzyme by adding a phosphate group.
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malignant
Invasive tumor that may spread.
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metaphase
Mitotic phase during which chromosomes are aligned at the spindle equator.
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metastasis
Spread of cancer from the place of origin throughout the body; caused by the ability of cancer cells to migrate and invade tissues.
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mitosis
Process in which a parent nucleus produces two daughter nuclei, each having the same number and kinds of chromosomes as the parent nucleus.
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nucleosome
Process in which a parent nucleus produces two daughter nuclei, each having the same number and kinds of chromosomes as the parent nucleus.
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prophases
Mitotic phase during which chromatin condenses so that chromosomes appear; chromosomes are scattered.
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signal
Molecule that stimulates or inhibits an event in the cell cycle.
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sister chromatid
One of two genetically identical chromosomal units that are the result of DNA replication and are attached to each other at the centromere.
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somatic cell
Body cell; excludes cells that undergo meiosis and become sperm or egg.
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spindle
Microtubule structure that brings about chromosomal movement during nuclear division.
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spindle equator
Disk formed during metaphase in which all of a cell's chromosomes lie in a single plane at right angles to the spindle fibers.
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telomere
Long, repeating DNA sequence at the ends of chromosomes; functions like a cap and keeps chromosomes from fusing with each other.
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telophase
Mitotic phase during which daughter cells are located at each pole.
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tumor
Cells derived from a single mutated cell that has repeatedly undergone cell division; benign tumors remain at the site of origin, while malignant tumors metastasize.
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