Amyl Nitrate

  1. Class
    Vasodilator/Cyanide Antidote
  2. Description
    Amyl Nitrite is potent vasodilator and an antidote for cyanide poisoning
  3. Mechanism of Action
    • Amyl Nitrate causes the oxidation of hemoglobin methemoglobin. Methemoglobin reacts with cyanide ion form cyanomethemoglobin, which can be enzymatically degraded.
    • Removes cyanide from the blood.
  4. Onset of Action
    • Onset:10-30 second

    • Peak:30 second

    • Duration:3-5 min

    • Half life:NA

  5. Indications
    Cyanide poisoning (bitter almond smell to breath
  6. Contraindications
    None in treatment in cyanide poisoning
  7. Precautions
    Has tendency for abuse, hypotension.
  8. Side Effects
    • headache
    • hypotension
    • Dizziness
    • nausea
    • tachycardia
    • flushing
    • cold sweats
    • syncope
    • orthostatic changes
    • weakness
    • vomiting.
  9. Adult Dose
    Break inhalant and inhale, administer as needed
  10. Pedi-Dose
    Break inhalant and inhale, administer as needed
  11. Max Dose
    As needed
  12. Routes of Administration
    Inhalation
  13. How Supplied
    Glass Inhalant
Author
RLESLIE
ID
94120
Card Set
Amyl Nitrate
Description
Paramedic Drugs
Updated