Parkinson's Disease

  1. Parkinson's disease is a disorder of ______ system of the brain involving in particular, the ______.
    • extrapyramidal
    • basal ganglia
  2. Parkinson's disease affects men and women equally. (Yes or No)
  3. Death of patients with Parkinson's are usually caused by ________.
    Immobility; e.g., aspiration pneumonia, cardiovascular disease.
  4. The pathologic hallmark of Parkinson's disease is __________ bodies within the _______ cells of the substantia nigra.
    • Lewy bodies (i.e., intraneuronal inclusion bodies)
    • dopaminergic cells
  5. Clinical manifestations seem to be associated with a progressive decrease of _______, and inhibitory neurotransmitter, and thhe relative increase of ________, an excitatory neurotransmitter.
    • DA
    • ACh
  6. Clinical Presentation of Parkinson's Disease
    - The Four Classical Features
    • Tremor
    • Muscle
    • Bradykinesia
    • Postural Disturbances
  7. Associated symptoms (10) of Parkinson's disease
    • handwriting abnormalities
    • drooling
    • seborrhea
    • speech disturbances (soft, monotone voice)
    • dysphagia
    • constipation
    • munbness and paresthesia
    • anxiety
    • depression
    • dementia
  8. No cure is known for parkinsonism; therefore, treatment is only symptomatic. (True or False)
Card Set
Parkinson's Disease
Treatment of Parkinson's