Solid tissue cell types

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    Lymphoma- MANY lymphoblast cells with prominent nucleoli
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    Eosinophilic inflammation (> 15% Eos)- think allergy, parasite, etc.
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    Mast cell- Mast cell tumors are common in dogs but we will also see them in inflammatory reactions, especially in skin, airway or reproductive tract. Remember that they are characterized by large numbers of purple granules and abundant cytoplasm.
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    Lymph node aspirate
    Epitheliod cells in the lymph node is an inappropriate place for them to be. SCC metastasized to l.n.
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    Epitheliod cell pleomorphism. Much variability- signs of malignancy
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    Normal epitheliod cells. Uniform. Exceptions: Round cell tumors with be uniform.
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    Monotonous population of cells. Fibrosarcoma in a dog.
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    Epitheliod cells of a SCC. Inflammation is not typically present with the exception of SCC's because of keratin stimulation of an inflammatory rxn.
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    Cellular piling (may suggest malignancy)
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    Large, abnormal nuclei with abnormally clumped chromatin. Signs of malignancy.
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    Multiple, large nucleoli= malignancy
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    Multiple, large nucleoli= malignancy
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    Multiple, large nucleoli= malignancy
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    Cellular piling and variability= malignancy
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    Abnormal mitotic figures= malignancy
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    Abnormal mitotic figures= malignancy
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Card Set
Solid tissue cell types
Cell morphologies of solid tissue aspirates