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Define macule.
- Circumscribed area of epidermis or mucosa distinguished by
- color from its surroundings
Is neither elevated nor depressed, be of any size
Lesions <1cm in diameter
Ex: oral melanotic macule, amalgam, India ink/pencil tattoos
“Pigmented Lesion”
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Define patch.
Circumscribed area larger than a macule
Is neither elevated nor depressed
Color, texture, or both
Ex: lichen planus, mucous patch of secondary syphilis
“White Lesions”
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Define erosion.
soft tissue lesion in which the epithelium ABOVE the basal cell layer is denuded
moist and slightly depressed
result from a broken vesicle, epithelial breakdown, or trauma
mucocutaneous erosions
ex. pemphigus, erosive lichen planus, erythema, multiforme
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Define ulcer.
an uncovered wound of cutaneous/mucosal tissue
exhibits tissue disintegration and necrosis
ulcers extend deeper than erions BEYOND the basal layer of of epithelium
ex. apthous stomatitis, infection by viruses (herpes simplex, smallpox, chickenpox and shingles)
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Define wheal.
an edematous papule or plaque resulting from acute extravasation of serum
only slightly raised
occur most commonly in persons with allergies
develops as a result of histamine release from mast cells/complement cascade
ex. from insect bites, allergy to food, mechanical irritation
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Define scar.
a permanant mark remaining after a wound heals
infrequently found in oral cavity
when they occur, an intraoral scar is usually lighter than the adjacent mucose
histologically more dense than adjacent epithelium
ex. fibrotic scar tissue from oral surgery, burns, or intraoral trauma
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Define fissure.
normal or abnormal linear cleft in the epidermis
affects the tongue, lips, and periooral tissues
variant of normal or disease
diseased result when pathogenic orgs infect a fissue -- cause pain, ulceration and inflammation
is a variation of normal associate with dry mouth and dehydration
ex. angular cheilitis
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define sinus.
has 2 meanings:
- 1. normal recess or cavity such as the frontal or maxillary sinus
- 2. an abnormal dilated tract that leads from a suppurative cavity, cyst or abscess to the surface of the epidermis
ex. actinomycosis
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Define papule.
superficial, elevated, solid lesion <1cm in diameter
may be attached by a stalk or firm base
often represents a benign or slow-growing lesion
ex. sqamous papilloma
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Define plaque.
- a flat, solid, raised area > 1cm in diameter
- plaques may extend deeper into the dermis than papules
- edges may be sloped and sometimes surface keratin proliferates
ex. lichen planus, leukoplakia, or melanoma....
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Define nodule.
- a solid mass of tissue that has the dimension of depth
- like papules, are <1cm in diameter; however, extend deeper into the dermis
- asymptomatic or painful and usually are slow growing
- overylying epidermis is usualy nonfixed
- ex. benign mesenchymal tumors: fibroma, lipoma...
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Define tumor.
- a solid mass of tissue >1cm in diameter, has dimension of depth.
- also represent a neoplasm - uncontrolled and progressive multiplication of cells that have no physiologic use
- benign or malignant
- benign grow more slowly and ar eless aggressive, do not metatasize, have well-defined margins
- malignant spread rapidly, comprised of aberran neoplastic cells
- carcinoma: malignant cancer of epithelial tissue
- sarcoma: malignant cancer of embryonic connective tissue origin
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Define vesicle.
- circumscribed, fluid-filled elevation in the epidermis <1cm in diameter
- fluid consists of lymph, serum, blood, or infecitous agents
- common in viral infections such as herpes simplex, chickenpox
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define pustule.
- circumscribed elevation filled with purulent exudate resulting from an infection <1cm in diameter, may be preceded by vesicel or papule
- creamy white or yellowish, often associated with an epidermal pore (pimple) represented by a pointing abscess
- ex. herpex zoster
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Define bulla.
- a vesicle that is >1cm in diameter
- accumulation of fluid in epidermal-dermis junction of split in epidermis
- ex. pemphigus, pemphigoid, burns, frictional trauma
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Deinfe cyst.
- an epithelial-lined mass located in the dermis, subcutaneous tissue, or bone
- result from entrapment of epithelium that grow to produce a cavity
- range from a few mm to several cm in daimeter
- ex: gingival cyst, later periodontal cyts
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Define crust.
- dried exudate, excretion or secretion of skin or mucosea
- rarely are intra-orally
- often on lips
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Define scale.
- dried epithelium that is superficially located - on the surface
- rarely occur intra-orally
- often on lips
- "epithelial flakes"
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Define nevus.
a birthmark or a mole on the skin, esp. a birthmark in the form of a raised red patch
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Define petechiae.
a small red or purple spot caused by bleeding into the skin
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Define purpura.
a rash of purple spots on the skin caused by internal bleeding from small blood vessels.• [with adj. ] any of a number of diseases characterized by such a rash : psychogenic purpura.
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