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Causative in neonates?
GBS
E Coli
Causative in child less than 5
S. pneumoniae
N meningitidis
Hib
greater than 5 yo
S. pneumoniae
N. meningitidis
Viral-?
and treatment
neonatal- HSV
Child- enterovirus, adenovirus
acyclovir 60mg/kg/d
Bacterial?
WBC- 400-100K
PMNs >90
glucose < .5 serum
protein 80-500mg/dl
smear +!
prophylaxis of mothers dosage is GBS +
PCN or AMP (2g iv x1 +1g iv q4h during labor)
screen at 32-35 wks
vaccination for meningitis
streptococcus pneumoniae- (leading cause in childhood)
vaccine is Prevnar (PCV7)- covers 7 serotypes
Empiric treatment in neonates
Amp + (gentamicin of cefotaxime)
if GBS, L monocytogenes keep amp and 72 hours gent duration 10-21d
if comes back gram - (E coli, Klebsiella, enterobacter) give cefotaxime
Treatment in 1 month to 5 years
empiric: ceftriaxone and vancomycin
if
S. pneumoniae cont for 10-14d
N. meningitidis penicillin or amp of ceftriaxone x 7d
Hib- ceftriaxone 10-14d
treatment in children greater than 5
empiric treatment- ceftriaxone + vancomycin
same as 1-5 same agents
Author
Anonymous
ID
9069
Card Set
peds men
Description
meningitis
Updated
2010-03-04T06:27:48Z
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