Blood

• 1. granular cytoplam (multiple types of granules)
• 2. lobulated (2-4) nuclei

--phagocytize, form pus

• 1. large, pink granules (can see crystalloid body in EM, multishaded granules)
• 2. lobulated nuclei (2)

Dense, dark, large granules (look grainy on EM)

mast cells are similar, but their nuclei are round/oval and the cells may be spindle shaped

• 1. large size
• 2. acentric, kidney shaped nucleus (notable indentation)
• 3. lack of specific granules

• 1. small size
• 2. large acentric nucleus
• 3. narrow rim of cytoplams

• 1. nucleus is multilobed and folded on itself
• 2. "foamy" peripheral cytoplasm

• 1. Proerythroblast
• 2. basophilic erythroblast
• 3. polychromatic erythroblast
• 4. orthochromatophilic erythroblast
• 5. reticulocyte
• 6. Erythrocyte

• 1. large, spherical nucleus
• 2. one or two visible nucleoli
• 3. cytoplasm is mildly basophilic b/c of free ribosomes

• 1. smaller than proerythroblast
• 2. very basophilic cytoplasm
• 3. smaller, more heterochromatic nucleus

• 1. last cell capable of mitosis
• 2. hemoglobin production begins
• 3. cytoplasm gets gray, or dull lilac
• 4. smaller than basophilic erythroblast

• 1. small, deeply stained nucleus
• 2. begins to acquire acidophilia
• 3. retains slight basophilia

(normoblast)

• 1. nucleus extruded
• 2. acidophilic cytoplasm with trace of earlier gray

what's next? erythrocyte -- acidophilic, smaller, biconcave*

• 1. Myeloblast
• 2. Promyelocyte
• 3. ________ myelocyte
• 4. ________ metamyelocyte
• 5. ________ stab cell
• 6. neutro/baso/eosino

• 1. huge
• 2. nucleus is large, euchromatic, w/ 3-5 nucleoli
• 3. NO granules
• 4. basophilic cytoplasm
• 5. might have cytoplasmic blebs on periphery

• 1. nucleus indented
• 2. nucleoli
• 3. increased size
• 4. azurophilic granules
• 5. condensing chromatin

• 1. last cell capable of mitosis
• 2. elliptical nucleus

nucleus becomes progressively indented and heterochromatic

nucleus is elongate and aquires a U shape