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Albuterol Sulfate (Proventil)
- Classifications:
- -B2 selective sympathomimetic
- -beta agonist
- Indications:
- -Asthma
- -COPD
- -Wheezing
- -Reactive Airway Disease
- -Hyperkalemia
- Contraindications:
- - Not indicated in cardiac wheeze
- Adult:- Broncho-constriction/wheezing/hyperkalemia
- 2.5mg in 3mL NSS
- Administered nebulized with 5-8LPM of 02
- Pediatric:
- - Broncho-constriction/wheezing/hyperkalemia
- 2.5mg in 3mL NSS
- Administered nebulized with 5-8LPM of 02
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Atropine (Atropine)
- - Anticholinergic
- - Parasympatholytic
- - Hemodynamically compromised symptomatic bradycardia (non-ami)
- - Symptomatic Sinus Arrest or Block
- - AV block at the Junctional Level
- - Slow PEA
- - Asystole
- - Organophosphate poisoning, cholinesterase inhibiting pesticides, sarin, Parathion and certain chemical weapons (SLUDGEM symptoms)
- Contraindications:
- - Contraindicated with heart transplant as there is no parasympathetic connection to the heart due to the vagus nerve being severed
- Adult:- All cardiac indications
- 0.5 to 1.0mg IVP q 3-5 min up to max 3mg or 0.04 mg/kg rapidly
- Alternatively it can be given via ETT at 2.0 to 2.5x IV dosage
- - Organophosphate poisoning
- 1-2mg q 5min
- Pediatric:- All cardiac indications
- Max 0.04mg/kg - min dose 0.1mg
- 0.02 mg/kg IVP
- Alternatively can be given ETT at 2.0 to 2.5X IV dose
- - Organophosphate poisoning
- 0.05mg/kg IV q. 10-20 min
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Bumetanide (Bumex)
- Classifications:
- - Loop diuretic
- Indications:
- - Pulmonary edema
- - Fluid overloaded patient
- Contraindications:
- - None when clinically indicated
- Adult:- Diuretic
- 0.5 - 2.0mg IV Push given over 2 minutes q 2-3 hours
- Note - 1mg of Bumex = 40mg of Lasix
- Max dose 10mg per day
- Pediatric:
- - Not recommended for pediatric patients
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Diazepam (Valium)
- Classifications:
- - Benzodiazepine
- - Anticonvulsant; Sedative-hypnotic
- Indications:
- - Seizures
- - Acute Agitation
- - Cocaine Overdose
- Contraindications:
- - Contraindicated with CNS depression and respiratory depression
- - Use caution in elderly patients
- Adult:- Seizures
- 5mg IV push SLOWLY
- - Cocaine overdose/Acute agitation
- 5-10mg IVpush SLOWLY
- Pediatric:- Seizures
- 0.1mg/kg IV push
- 0.5mg/kg PR
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Diphenhydramine (Benadryl)
- Classifications:
- - Antihistamine
- - Anticholinergic (Antimuscarinic)
- Indications:
- - Relief of symptoms from allergic reactions
- - Anticholinergic - used to treat acute dystonic response (stiff gait, cog wheel rigidity), extrapyramidal reactions to antipsychotic drugs (Haldol, Thorazine, Compazine)
- Contraindications:
- - None when clinically indicated
- Adult:- Allergic reaction/Dystonic response
- 25-50mg IV push or deep IM
- Pediatric:- All indications
- 1mg/kg IV push or IM
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Dexamethasone Sodium Phosphate (Decadron)
- Classifications:
- - Synthetic Steroid (long-lasting glucocorticoid)
- Indications:
- - Asthma / Croup
- - Anaphylaxis or allergic state
- - Brain tumor with edema
- - Alternative to Solu-Medrol
- Contraindications:
- - Contraindicated with systemic fungal infection
- Adult:- All indications
- 10mg IV push or IM
- Pediatric:- Croup
- 0.6mg/kg IM or IV
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Epinephrine (Adrenalin)
- Classifications:- Vasopressor
- - Catecholamine
- Indications:
- - Bradycardia
- - Cardiac Arrest
- - Anaphylaxis
- - Asthma
- Contraindications:
- - Outside of cardiac arrest, administer cautiously in presence of older age, debilitation, hyperthyroidism, hypertension
- - Use with caution in patients with angina, hypertension, CAD
- - May cause severe hypertension in those taking beta blockers
- Adult:
- - Anaphylaxis
- 0.3 - 0.5mg SC (1:1000 Concentration)
- - Asthma
- 0.3 - 0.5mg SC (1:1000 Concentration)
- - Cardiac Arrest
- 1mg IV push (1:10,000 Concentration) q 3-5 min
- 2.0X to 2.5X IV dose for ETT administration (mix 2.0-2.5mg in 10ml of NSS)
- - Bradycardia
- 1-10mcg/min IV Drip; 1mg to 500mL
- Pediatric:- Cardiac Arrest
- 0.01mg/kg IV Push (1:10,000 concentration) q. 3-5min
- - Anaphylaxis
- 0.01 mg/kg IV Push (1:10,000 concentration)
- 0.01 mg/kg SC (1:1,000 concentration)
- - Bradycardia
- 0.01 mg/kg IV push x1 dose only (1:10,000 concentration)
- Max dose of 1mg
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Furosemide (Lasix)
- Classifications:
- - Loop Diuretic
- Indications:
- - Pulmonary edema (acute)
- - Hyperkalemia (not acute treatment)
- - Acute renal failure
- Contraindications:
- - Relative contraindicated with allergy to sulfa drugs, hypotension with pulmonary edema, and dehydration
- - Caution with severe renal disease, acute MI
- Adult:- Acute pulmonary edema (BP > 120 systolic)
- 20mg IVP - standing orders
- 1.0mg/kg IV push slowly
- Pediatric:- Pulmonary edema/Hypertension
- 1mg/kg IV push q 6-12 hrs
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Ipratropium Bromide (Atrovent)
- Classifications:
- - Anti-Cholinergic
- - Bronchodilator
- Indications:
- - COPD
- - Asthma
- Contraindications:
- - None if clinically indicated
- Adult/Pediatric:0.5mg in 2.5ml NSS - 0.02% solution
- Nebulized with 6-8 liters of 02
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Levalbuterol (Xopenex)
- Classifications:
- - B2 selective sympathomimetic
- - Beta agonist
- Indications:
- - Asthma
- - COPD
- - Wheezing
- - Reactive airway disease
- Contraindications:
- - None when clinically indicated
- Adult:- Broncho-constriction/wheezing
- 1.25mg in 3ml NSS for more severe wheezing (acute setting)
- Administered nebulized with 5-8 LPM of 02
- - Other doses
- 0.63mg in 3ml NSS for moderate wheezing (home therapy)
- Pediatric:1.25mg in 3ml NSS for more severe wheezing (acute setting)
- 0.31mg in 3ml NSS for pediatric patients (home therapy)
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Lorazepam (Ativan)
- Classifications:
- - Benzodiazepine
- - Anti-convulsant
- - Sedative-hypnotic
- - CNS depressant
- Indications:
- - Control seizure disorders emergent and non-emergent
- - Relieve anxiety
- Contraindications:
- - Contraindicated with known hypersensitivity to benzodiazepines
- - Caution in elderly patients, very ill patients or patients with reduced pulmonary reserve as hypoventilation, hypoxia
- Adult:- Seizure/sedation/relieve anxiety
- IV injection - 1.0mg to 2.0mg
- IM injection - 2.0mg up to 4.0mg
- Pediatric:
- -
Seizures - 0.05 - 0.1mg/kg IV push
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Magnesium Sulfate (Magnesium Sulfate)
- Classifications:
- - Antiarrhythmic
- - Smooth muscle relaxant
- Indications:
- - Torsades de Pointes
- - Pulseless VT/VF (refractory) after Amiodarone or Lidocaine
- - Eclampsia-seizures due to toxemia of pregnancy
- - Asthma
- Contraindications:
- - None when clinically indicated
- Adult:- Alive Dose - Torsades de Pointes - VTach
- 1-2g IV drip over 5-15 minutes (BP dependant)
- - Dead Dose - Recurrent or refractory v-fib / pulseless VTach / Torsades
- 1-2g IVP
- -Asthma
- 2g IV drip given over 20 minutes
- -Pre-eclampsia/eclampsia
- 2-4g IV given over 3-5 minutes
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Methylprednisolone (Solu-Medrol)
- Classifications:
- - Glucocorticoid steroid (medium-acting)
- Indications:
- - Asthma
- - Neurogenic Shock (controversial)
- - Acute spine cord injury
- Contraindications:
- - Caution with GI bleeding, diabetes mellitus
- Adult:
- -
Anaphylaxis, Asthma - 125mg IV Push
- Pediatric:- Anaphylaxis, Asthma
- 2mg/kg dose IV Push
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Midazolam Hydrochloride (Versed)
- Classifications:
- - Benzodiazepine
- - Sedative-hypnotic (rapid onset, short acting)
- Indications:
- - Pre-medication before cardioversion
- - Sedation
- - Seizures
- Contraindications:
- - Use caution with decreased respiratory drive; AMS
- - Liver disease / cirrhosis
- Adult:- Pre-intubation/Sedation
- 0.1mg/kg IV Push
- Typical dose 5mg-10mg IV Push
- - Seizures when no IV access is avail
- 2-5mg IM
- -Induction Agent
- 0.2mg/kg IV push - 7-10mg avg. adult
- Pediatric:- Seizures without IV access
- 0.1mg/kg IM
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Morphine Sulfate (Morphine)
- Classifications:
- - Narcotic
- - Analgesic
- Indications:
- - Pain (burns, MI, and others)
- - Cardiac chest pain (refractory to nitrates)
- Contraindications:
- - Contraindicated with existing respiratory depression
- - Caution with COPD, CNS depression, hypotension
- Adult:- Pain (MI, sickle cell and other)
- 2-5mg IV Push q. 5 minutes until desired effects
- - Pain (Burns)
- 5-10mg IV Push q. 5 minutes until desired effects
- Often high dose morphine is required for pain relief
- Pediatric:- Pain (all indications)
- 0.1mg/kg IV Push
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Naloxone (Narcan)
- Classifications:
- - Opioid Antagonist (shorter acting)
- Indications:
- - Reverse pre-operative opiate induced sedation
- - Opioid/Opiate overdose
- Contraindications:
- - In apneic, narcotized patients, apply BVM resuscitation prior to administration of Narcan.
- - Too much Narcan can induce withdrawal, only administer enough to maintain respiratory drive and oxygenate patient
- Adult:- Opiate overdose
- 0.4 - 2.0mg IM/IV/SC/Inter-Nasal
- Pediatric:- Opiate reversal (0-5 years old or <20kg)
- 0.1 mg/kg IV/SC/ETT q. 3 minutes until response
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Nitroglycerin (Nitrostat, Nitrospan, Nitrodisc, Nitrodur, Tridil)
- Classifications:
- - Nitrate
- - Vasodilator
- Indications:
- - MI (without right ventricular involvement)
- - Angina pain
- - First line agent for pulmonary edema from CHF
- Contraindication:
- - Hypotension
- - Bradycardia (relative)
- Adult:- All indications:
- 0.4mg (2% solution) SL spray administer on mucus membranes of mouth (under toungue)
- 0.4mg (1/150grains) SL tablet q. 3-5 minutes
- 1-2 inches as on ointment/paste - apply to skin without hair - avoid self exposure
- 10-20mcg/min IV drip mixed 50-100 mg in 250mL
- Increase by 5-10mcg/min q. 5-10 minutes until desired response
- Pediatric:No prehospital administration recommended
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Oxygen (Oxygen)
- Classifications:
- - Naturally occurring gas
- Indications:
- - Confirmed or suspected hypoxia
- - Ischemic chest pain
- - Respiratory insufficiency
- - Confirmed or suspected carbon monoxide poisoning and other causes of decreased tissue oxygenation (cardiac arrest, shock)
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Terbutaline (Brethine)
- Classifications:
- - B2 agonist
- - Bronchodilator; smooth muscle relaxant
- Indications:
- - Asthma
- - Bronchospasms
- - Premature labor
- Contraindications:
- - Caution with hypertension and ventricular arrhythmias
- Adult:- Asthma/Bronchospasm/Premature labor
- 0.25mg SQ to start, wait 15 min repeat if necessary
- Pediatric:Not recommended for pediatrics in pre-hospital setting.
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