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Nervous system vs. Endocrine system
rapid activity (movement and thinking) vs. slow activity (growth)
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Nervous System
a coordinating system of the body composed of a group of highly specialized cells for conducting nerve impulses to a center so responses can be made
the nervous system provides a control for the rapid activities of the body
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Major Subdivisions of NS
- CNS - brain and spinal cord
- PNS
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Nervous Tissue functions
- 1) to receive stimuli from the environment (receptor)
- 2) to transform these stimuli into nerve impulses (receptor)
- 3) to transmit these impulses to the proper nerve center of the body (neuron)
- 4) to process the information and determine the appropriate response (brain, spinal cord)
- 5) this response is transmitted to the effector organ (neuron)
- 6) the effector organ carries out the response (effector)
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Principal cells of the NS
neuron and neuroglia
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Neuron
functional unit of the NS
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Dendrites
cytoplasmis extensions that receive information and transmit it toward the cell body
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Cell body or soma
contains the nucleus and controls the metabolic activity of the neuron
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Axon Hillock
connects the cell body to the axon
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Myelin
insulating substance which allows axons to conduct impulses faster
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Nodes of Ranvier
gaps between segments of myelin
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Synaptic terminals
swellings at the end of the axon, involved in neurotransmitter release
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Synapse
gap between the axon terminal of one neuron and the dendrite of another
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Neuroglia
supportive connective tissue that natures and protects the neurons
Schwann, Oligodendrocytes, Microglia, Astrocytes, Ependymal Cells, Satellite Cells
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Schwann Cells
neurolemmocytes
form fatty myelin sheaths around the most axons in the PNS only; this insulatory material is not continuous along the axon but is interrupted at the nodes of Ranvier; the nerve impulses jump from node to node as they travel down the axon, a conduction called saltatory conduction
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Oligodendrocytes
form similar myelin sheaths in the CNS only
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Microglia
phagocytic cells that migrate throughout the CNS removing debris; may migrate to areas where nervous tissue is injured
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Astrocytes
regulate the passage of molecules from blood to the brain; helps form the blood-brain barrier that regulates the passage of substances into the brain
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Ependymal Cells
line the brain chambers called ventricles and help form the choroid plexus; which produces cerebrospinal fluid
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Satellite Cells
support neuron cell bodies in ganglis of the PNS
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CNS Neuroglia
- astrocytes
- microglia
- oligodendrocytes
- ependymal cells
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PNS Neuroglia
- schwann cells
- satellite cells
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Classification of neurons
multipolar: 2 or more braches of the soma
bipolar: 2 branches of the soma
unipolar: 1 branch of the soma
SAME
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Afferent neurons
sensory
transmit sensory nerve impulses from receptors to the brain and spinal cord
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Efferent
Motor
convey motor nerve impulses from the brain and spinal cord to effectors (muscles and glands)
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Interneurons
Internuncial neurons
carry impulses from one neuron to another; makes up the majority of nerves in the body
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Action Potentials
travel the length of the axon and invade the nerve terminal, thereby causing the release of neurotransmitter into the synapse
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Pituitary Gland
hangs by a stalk from the hypothalamus of the brain
posterior and anterior
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Posterior Pituitary Gland
appears fibrous
neurons produce ADH, and antidiuretic hormone, and oxytocin
ADH is stored in, and released from, the post. pit. gland in response to neural stimulation from the hypothalamus via the hypothalamohypophyseal system
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Anterior Pituitary Gland
appears glandular
develps from epithelial tissue that pinches off from the roof of the embryo's mouth
produces the hormones it secretes: growth hormone, ACTH, thyroid-stimulating hormone, luteninizing hormone, follicle-stimulating hormone, prolactin, melanocyte-stimulating hormone
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Thyroid Gland
shaped like a bowtie or shield and lies just below the Adam's apple in the front of the neck
thryoxine helps set basal metabolic rate by stimulating the rate of cell respiration
in children, thyroid hormones also promote growth and stimulate maturation of the CNS
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Parathyroid Glands
four small glands attached to the posterior surface of the thyroid gland
produces parathyroid hormone, which is involved in calcium homeostasis
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Adrenal Glands
located above each kidney
each gland is composed of an inner portion (medulla) and an outer layer (cortex)
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Adrenal Cortex
hormones from adrenal cortex are collectively referred to as corticosteroids
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Adrenal Medulla
secretes epinephrine and norepinephrine in response to the ANS
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Pancreas
located adjacent to the stomach and is connected to the duodenum by the pancreatic duct
secretes insulin and a variety of digestive enxymes into small intestine
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Ovaries and Testes
produce androgen
associated with secondary sexual characteristics
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Pineal Gland
secretes melatonin
regulates biological clocks
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Hormone Agonist
any chemical that can bind to receptor proteins and mimic the effects of the hormone
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5 lobes of the brain
frontal, parietal, occipital, temporal, and insula
insula lies within the depths of the lateral sulcus
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Cerebrum
largest part of the brain consisting of two hemispheres
gyri: convolutions of the cerebrum separated by sulci
contains various fissures and large sulci
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Longitudinal fissure
separates the right and left hemispheres and is occupied by the falx cerebri
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Transverse fissure or sulcus
separates the cerebrum and cerebellum and is occupied by the tentorium cerebelli
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Lateral sulcus or fissure
separates the temporal lobe from the rest of the cerebrum
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Central sulcus
the precentral (motor) and postcentral (sensory) gyri
the primary motor cortex is precentral gyrus; it lies anterior to the central sulcus
the primary sensory cortex is the postcentral gyrus; it lies posterior to the central sulcus
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Basal Ganglia (Nuclei)
constitutes the central gray matter of the cerebrum
- function in control of movement and posture
- - diesease involve disturbances in voluntar muscular control (Parkinson's, Huntington's)
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Thalamus
most important sensory relay center of the brain
it sends incoming impulses from the receptors of the body to the cerebral cortex
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Hypothalamus
- it lies between and is associated with the:
- 1) Optic Chiasma: where optic tracts (CNII) cross
- 2) Mammillary bodies: sensory synaptic station
- 3) Pituitary Gland: projects inferior from it and secretes many hormones
Functions in the regulation of visceral activity (body temperature, carb and lipid metabolism, sleep, sexual activity, and emotions)
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Medulla Oblongata
part of the brain directly continuous with the spinal cord and will contain most of the ascending and descending tracts of the spinal cord
represents an area where pyramidal tract fibers lie, called the pyramids: contain several nuclei involved in the regulation of the vital body activities: respiratory, cardiac (HR), vasomotor (BP)
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Pons
acts as a bridge connecting the right and left cerebellar hemispheres
relay impulses from the cerebral cortex to the cerebellum
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Cerebellum
little brain
connects with the midbrain, pons, and medulla oblongata; consists of two hemispheres separated by a median vermis; outer cortex contains folia separated by fissures, folia means leave; internally presents white matter branching in the form of a tree, called the arbor vitae; functions to coordinate muscular activity, regulate muscle tone, and maintain muscle equilibrium
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Corpora Quadrigemina
- consists of 4 elevations
- - superior colliculi involved in the pathway of vision
- - inferior colliculi involved in the pathway of hearing
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Brainstem
- midbrain
- pons
- medulla oblongata
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Gray Matter of the spinal cord
area of cell bodies within the CNS
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White Matter of the spinal cord
area of axons or fibers within the CNS
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Dorsal Root
arises from the dorsal surface of the spinal cord; contains sensory neurons only
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Dorsal Root Ganglion
enlarged part of the dorsal root
area of cell bodies outside the CNS
contains cell bodies of sensory neurons
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Ventral Root
arises from the ventral surface of the spinal cord
contains motor neurons only
joins with the dorsal root to form the SPINAL NERVE
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Spinal Nerve
divides into a larger ventral ramus which supplies the entire anterior trunk as well as the appendages
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Dorsal Ramus
smaller
supplies all the structure of the back
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Anatomy of the spinal cord
long cyndrical mass of nervous tissue that occuplies the upper 2/3 of the vertebral canal; connected to the brain superiorly where it is continuous with the medulla oblongata and extends to the level of LV2; presents enlargements in the cervial and lumbar regions where cell bodies of the neurons for the upper and lower limb are located; lower end of the cord is termed CONUS MEDULLARIS; below LV2 is the CAUDA EQUINA which consists of the very long roots of the lower spinal nerves which descend in a bundle from the conus medullaris
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Meninges
the brain and spinal cord are surrounded and protected by three layers of connective tissues, collectively termed meninges
from external to internal, dura mater, arachnoid mater, pia mater
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Dura Mater
outermost meninge composed of tough fibrous connective tissue; dura of the spinal cord extends from the foramen magnum where it is continuous with the dura mater that surrounds the brain and then courses inferiorly to the coccyx in the vertebral canal; this space external to the dura mater is the epidural space: contains adipose tissue in the form of globules of fat and veins and contains the vertebral venous plexus
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Arachniod Mater
intermediate meninge
delicate, loose, netlike membrane that extends from the foramen magnum where it is continuous with the cerebral arachnoid inferiorly through the vertebral column to coccyx; separated from the pia mater by the subarachnoid space which contains CSF
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Pia Mater
innermost meninge
very delicate connective tissue that adheres to the surface of the brain and spinal cord; extends from the foramen magnum to the coccyx
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PNS
periphery means along the outside
extends beyond the CNS, thus includes all the nervous tissue structures except the brain and spinal cord
most not protected by bone
composed of 12 prs of cranial nerves and 31 prs of spinal nerves
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Spinal nerves
- 8 prs of cervical
- 12 prs of thoracic
- 5 prs of lumbar
- 5 prs of sacral
- 1 pr of coccygeal
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Chemoreceptors
sensitive to chemical substances in the immediate area
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Mechanoreceptors
stimulated by mechanical forces like pressure
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Proprioreceptors
sense the degree of muscle contraction, the movement of ligaments, and the stretch of tendons
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Thermoreceptors
stimulated by changes in temperature
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Pain receptors
nocioceptors
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Photoreceptors
detect light
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Somatic senses
senses that are associated with the skin, muscles, and joints
proprioception is a sense of knowing the position of the limbs
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Special senses
sense organs for taste, smell, vision, equilibrium, and hearing
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Skin
contains receptors for touch, pressure, pain, and temperature
adaptation occurs when a receptor becomes accustomed to stimulation and stops generating impulses, even though the stimulus is still present
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Taste
taste buds are groupings of cells found in the tongue epithelium and open at a taste pore; recent functional and molecular data have found that there is no tongue "map": where certain areas are responsive to the 5 basic modalities- bitter, sour, sweet, salty, and umami - all modalities are present in all areas of the tongue
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Olfaction
our sense of smell is dependent on olfactory cells found in the roof of the nasal cavity
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Vision
- eyeball is an elongated sphere about 2.5cm in diameter and has 3 layers:
- -sclera: outer layed, white and fibrous except for the transparent cornea known as the window of the eye
- - choroid: middle, dark, think brown layer; toward the front it thickens and forms the ringshaped ciliary body which contains ciliary muscle which controls the shape of the lens for near and far vision; it becomes thin, circular, muscular, pigmented diaphragm called the IRIS which regulates the size of the pupil
- - retina: inner layer containing rods and cones, there are no cones or rods where the optic nerves passes through which is called the blind spot; vision is most acute in the fovea centralis
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Diseases and preventing loss of vision
in diabetic retinopathy, capillaries to the retina burst and blood spills into the viteour humor, this blinds people between 20 and 74 yrs old
galucoma occures when the eye drainage system fails so that fluid builds up, destroys nerve fibers that are responsible for peripheral vision
most common cause is careless use of contacts, increases cataracts in heavy smokers, wear sunglasses that absorb UV light, glasses with large lenses offer better protection than smaller
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Ear functions
hearing and equilibrium (balance)
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Outer ear
pinna (external flap made of cartilage and skin) and the auditory canal
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Middle ear
begins at the tympanic membrane (eardrum) and ends at a wall containing the oval window (the round window is near this area and allows fluid in the cochlea to move)
- 3 bones are between the eardrum and oval window:
- - malleus (or hammer): attaches to the tympanic membrane
- - incus or anvil
- - stapes or stirrup: contacts the oval window
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Inner ear
semicircular canals and the vestibule are involved with equilibrium; cochlea is involved with hearing; cochlea appears snail-shaped and is lined with small hairs called stereocillia; the movement of these hairs transmits sensation to our brain to interpret sound; eustachian tube (auditory tube) extends from the middle ear to the nasopharynx - this permits equalization of air pressure when we swallow or yawn
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Preventing loss of hearing
limiting exposure to loud noises; any noise over 80 decibels may damage hair cells of the organ of corti and cause them to disappear completely; tinnitus (ringing in ears); anticancer drugs or certain anitbiotics may increase sensitivity to loud noises
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Effectors of the body
muscles: smooth, cardiac, skeletal
glands: endocrine, exocrine
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ANS
responsible for the control of smooth muscle, cardiac muscle, endocrine glands, and exocrine glands
autonomy means self-government
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