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Class
Sympathetic agonist
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Description
Isoproternol is a synthetic catecholamine. Acts primarily on beta adrenergic receptors
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Mechanism of Action
Potent synthetic catecholamine that increases heart rate in bradycardias that are refractory to atropine. Increase cardiac contractile force, bronchodilation.
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Onset of Action:
Onset: Immediate Peak: <1 min Duration: Varies Half Life: <1.5 min
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Indications
Bradycardias refractory to atropine
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Contraindications
Should not be used to increase blood pressure in cardiogenic shock
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Precautions
Ventricular irritability, can be deactivated by alkaline solutions, used with caution after recent MI, external pacing should be used instead if available.
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Side Effects
Headache, palpitation, tachydysrthythmias, tremors
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Adult Dose
1mg placed in 500ml of D5W infused at 2 -10 ug/min and titrated to desired effects or PVC’s occur
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Routes of Administration
IV/IO
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