One of the most commonly used agents to treat hypotension associated with cardiogenic shock; chemically related to epinephrine and norepinephrine.
Mechanism of Action
Increases cardiac contractile force and thus cardiac output when used from 2-10mcg/kg/mini. The drug of choice for the management of cardiogenic shock; increases the systolic blood pressure and the pulse pressure. Doses exceeding 10mcg/kg/min cause peripheral vasconstriction.
Should not be used as the sole agent in management of hypovolemic shock until after adequate fluid resuscitation has been attempted
presence of tachydysrhythimias or V-Fib , deactivated by sodium bicarbonate, if taking monoamine oxdase inhibitors ( a type of depressant), dosage should be reduced to avoid possible hypertension crisis
Dosage and Administration
400mg Dopamine in 250 milliters of D5W concentration of 1600mcg per ml; effects are dose-dependent, start at 2-20mcg/kg/min and titrate to effect. Only by IV infusion and is to be piggybacked
Pediatric Dose-2-20mcg/kg/min and titrate to effect