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components of the olfactory system
- olfactory mucusa
- olfactory N
- olfactory bulbs
- olfactory tracts
- olfactory cortex
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olfactory mucosa
- in sphenoethmoid recess
- PSCC epithelium
- contains olfactory (bowman's) glands- secrete fluid
- olfactory cells-olfactory receptors, bipolar, constantly replaced, unmyelinated
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olfactory nerves
- axons of olfactory cells
- enter cranial cavity thru cribiform foramina of ethmoid bone
- terminate in olfactory bulb as glomeruli
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olfactory bulbs
- extension of the brain
- made mainly of mitral cells- innervate glomeruli
- few tufted cells-also innervate glomeruli
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olfactory tract
- mostly mitral cells, few tufted
- most lead thru lateral olfactory stria, few to anterior perforated surface
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lateral olfactory area
- input thru lateral olfactory stria, makes primary olfactory area
- uncus- anterior parahippocampal gyrus)
- limen insula
- amygdala
- allows you to experience smells
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olfactory association area
- alows identification of odors
- adjacent to primary olfactory cortex
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anterior perforated substance
- between lateral and medial olfactory stria
- neurons connect to limbic structures
- not incolved in concious olfaction
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olfaction influences on emotions, memory, and autonomic function
- olfactory neurons project to areas of cerebral cortex, hypothalamus, and reticular system
- influence emotional and visceral status of an individual
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testing olfactory system
- each nostil should be tested separately
- use recognizable odor
- non-irritative odor, otherwise you would be testing pain receptors
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causes of olfactory injuries
- fractures of ethmoid bone
- meningioma in floor of anterior cranial fossa
- olfactory hallucinations
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uncinate seizures
- convulsive movements of lips and tongue
- disagreable olfactory hallucinations
- confusion
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external ear
- pinna- auricula
- external auditory meatus- bony
- external auditory canal- fleshy + bony
- collects air vibrations and transmits them to the tympanic membrane
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middle ear
- tympanic membrane
- malleus
- incus
- stapes
- oval window
- round window
- vibrations transferred thru ossicular chain to oval window
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muscles of middle ear
- tensor tympani (trigeminal N)
- stapedius (facial N)
- dampen loud noises/vibrations
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inner ear- osseous labyrinth
- tunnels in the petris temporal bone
- filled with perilymph
- semicircular canals- posterior part
- vestibule- middle part
- cochlea- anterior part (2 3/4) turns
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inner ear- membranous labyrinth
- membrane tubes in osseous labyrinth
- filled with enodlymph
- semicircular ducts- within semicircular canals
- utricle- connects to semicircular ducts
- saccule- connects to cochlear ducts via ductus reunions
- cochlear duct
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cochlear canal
- scala media- cochlear duct, middle space
- scala vestibuli-- superior to scala media, filled with perilymph, continuous with oval window
- scala tympani- inferior to scala media, filled with perilymph, continuous with scala vestibuli at helicotreme, continous with round window
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cochlear duct
- scala media
- vestibular membrane- b/t scala media and vestibuli
- stria vascularis- epithelial lining over vasculature, outer wall, produces endolymph
- basilar membrane- b/t scala media and tympani, includes organ of corti
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organ of corti
- mechanoreceptor
- support cells- border cells, phalangeal cells, pillar cells, and cells of hensen
- tectorial membrane- gelatinous membrane along organ of corti, tips of hair cells embedded here
- sensory cells
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inner hair cells
- single row
- attached to chochlear nerve
- principal sensory cells
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outer hair cells
- three rows at basal turn increasing to five rows at apex
- innervated by chochlear nerve
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tonotopical organization of organ of corti
- high pitch- along basal turn
- low pitch- apical end
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auditory pathways- primary neuron
- cell bodies in spiral ganglia
- peripheral processes innervate hair cells
- central processes make cochlear division of VIII N, terminate in cochlear nucleus
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auditory pathways- secondary neurons
- cell bodies in cochlear nuclei
- processes project thru central auditory pathway
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contralateral auditory pathway
- axons project to contralateral side of pons
- -form the trapezoid body
- -some terminate in superior olivary nucleus
- -ascending fibers form lateral lemniscus, terminate in inferior colliculus, thru inferior brachium, into medial geniculate body of thalamus. axons thru internal capsule to form auditory radiations in primary auditory cortex
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ipsilateral auditory pathway
- secondary neurons in cochlear nucleus project to ipsilateral suprior olivary nucleus
- thru ipsilateral lateral lemnisculs, inferior colliculus, inferior brachium, medial geniculate body, and auditory radiations
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auditory cortex
- primary auditory cortex in floor of the lateral sulcus
- Heschl's gyrus- hears sounds, in transverse temporal gyrus
- brodmann's area 41, 42
- high hertz= medial
- low hertz= lateral
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auditory association cortex
- temporal lobe surrounding heschl's gyrus
- brodmann's area 22
- recognition and interpretation of sounds
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significance of bilateral pathway
unilateral damage above cochlear nuclei results in decresed hearing in both ears, but not total loss of hearing
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general function sof vestibular system
- maintain body equilibrium- posture and balance
- coordinate eye movements
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saccule and utricle
- parts of membranous labyrinth filled with endolymph
- each contains a macula- sensory epithelium, mechanoreceptors
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morphology of the macula
- hair cells- stereocilia projections with a single kinocilium embedded into the otolithic membrane
- otolithic membrane- gelatinous membrane with otolithes- crystals of protein and calcium carbonate
- dendrites of primary vestibular neurons- cell bodies in vestibular ganglion
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macula monitors which types of movement?
tilting movements in a linear plane
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anterior semicircular duct is oriented in which plane?
vertical
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lateral semicircular duct is oriented in which plane?
30 degrees to the horizontal
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ampulla
- dilation at end of duct
- lateral semicircular duct has anterior ampulla
- contains crista ampullaris
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crista ampullaris
- mechanoreceptor for angular/rotational movement
- hair cells- stereocilia with single kinocilium embedded in cupula
- vestibular neurons in vestibular gangion
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ampullopedal flow of endolymph
flow toward the ampulla from the duct
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ampullofugal flow
flow away from the ampulla thru the duct
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flow of enodlymph in lateral duct
- ampullopedal movemnt facilitates crista
- ampullofugal movement inhibits crista
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what happens to the discharge of crista when the head maintains rotation at a constant velocity?
no net movement of endolymph so discharge returns to static rate
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vestibulospinal tract
- major motor control pathway
- ipsilateral
- terminates on interneurons or motor neurons
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descending medial longitudinal fasciculus
- ipsilateral and contralateral (bilateral)
- most terminate in cervical segments to influence neck muscles
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ascending medial longitudinal fesciculus
- permits visual fixation on stationary targets
- ipsilateral and contralateral
- influence cranial nerves VI, IV, and III
- allows both eyes to move together
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vestibular information to the archicerebellum influences:
- posture and balance
- neurons to vestibular nuclear complex, to vestibulospinal tract
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vestibulo-ocular/ vestibulokinetic reflex
- eyes slowly drift to the left (fixation on a target)- mediated by MLF
- eyes quickly move to the right (fixation on a new target)- not vestibular driven
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nystagmus
fast-slow eye movements
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roatation test of vestibular system
- patient seated, head tilted forward 30 degrees, rotate at a constant velocity to the RIGHT
- continue until crista reach static discharge, stop chair and have patient stand and focus on stationary object
- eyes should display left nystagmus, patient will fall to the right, past point to the right of the object
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Caloric test
- patient tilts head backwards 60 degrees
- irrigate external auditory meatus with warm or cool water
- response is COWS
- cool water= fast drift to opposite side
- warm water= fast drift to same side
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