-
PCO2
partial pressure of CO2
-
percent of CO2 carried in the plasma
0.1
-
the faster and more deeply the patient breaths the
more CO2 is blown off
-
as CO2 levels increase
blood pH decreases
-
as CO2 levels increase
blood PCO2 increases
-
a rise in PCO2 stimulates a rise in
respiratory rate
-
in metabolic acidosis the lungs attempt to compensate by
blowing off CO2
-
in metabolic alkalosis the lungs attempt to compensate by
retaining CO2
-
Most of the CO2 content in the blood is
HCO3-
-
-
CO2 content is an indirect measurement of
HCO3-
-
_____ is a measurement of the metabolic (renal) component of the acid-base equilibrium
HCO3-
-
in respiratory alkalosis the _____ excrete HCO3 in an attempt to lower pH
kidneys
-
the measure of the tension of O2 dissolved in the plasma
PO2
-
patients in whom venous blood mixes prematurely with arterial blood have a decrease in ____
PO2
-
the indication of the percentage of hemoglobin filled with O2
O2 saturation
-
when ___% to 100% of the hemoglobin carries O2 the tissues are adequately provided with O2
92
-
non-invasive method of determining O2 saturation
pulse oximetry
-
a negative base excess indicates
metabolic acidosis
-
a positive base excess indicates
metabolic alkylosis or compensation to prolonged respiratory acidosis
-
acidosis is present if the pH is less than
7.4
-
alkylosis is present if the pH is greater than
7.4
-
if the PCO2 is low in a patient who has been said to have acidosis the patient has
metabolic acidosis
-
if the PCO2 is high in a patient who has been said to have acidosis the patient has
respiratory acidosis
-
if the PCO2 is low in a patient who has been said to have alkylosis the patient has
respiratory alkylosis
-
if the PCO2 is high in a patient who has been said to have alkylosis the patient has
metabolic alkylosis
-
O2 saturation can be falsely increased by the inhalation of
carbon monoxide
-
In patients with COPD the stimulus to breathe is not triggered by CO2 levels but by
O2
-
Perform which test before performing an arterial puncture in the radial artery
Allen test
-
low pH, low HCO3-, low CO2
metabolic acidosis
-
low pH, high HCO3-, high CO2
respiratory acidosis
-
high pH, high HCO3-, high CO2
metabolic alkalosis
-
high pH, low HCO3-, low CO2
respiratory alkalosis
-
-
-
-
-
__|__|__/ (bottom) | |X \ chem 7
creatinine
-
X |__|__/ | | \ chem 7
Na
-
__|X |__/ | | \ chem 7
Cl
-
__|__|X / | | \ chem 7
BUN
-
__|__|__/ (bottom) X | | \ chem 7
K
-
__|__|__/ (bottom) |X | \ chem 7
HCO3-
-
__|__|__/ | | \ X chem 7
glucose
-
if bicarb is low you expect pCO2 to be
low
-
if pCO2 is high you expect bicarb to be
high
-
example of cause of non-anion gap metabolic acidosis
diarrhea
-
example of cause of anion gap metabolic acidosis
excessive alcohol consumption
-
non-anion gap metabolic acidosis is characterized by
loss of bicarb
-
anion gap metabolic acidosis is characterized by
gain of acid
-
-
-
-
normal creatinine
0.6-1.2
-
-
-
-
normal osmolality
275-295
-
primary etiology of respiratory acidosis
lungs fail to eliminate CO2
-
example of a cause of metabolic alkalosis
protracted vomiting
-
example of a cause of metabolic alkalosis
ingestion of a large quantity of base
-
in a metabolic alkalotic state will you have hypokalemia or hyperkalemia
hypokalemia
-
in a metabolic acidotic state will you have hypokalemia or hyperkalemia
hyperkalemia
-
primary etiology of respiratory alkalosis
lungs are eliminating too much CO2
-
in acute respiratory acidosis for every increase of pCO2 of 10mm pH decreases by
0.08
-
in chronic respiratory acidosis for every increase of pCO2 of 10mm, ph decreases by
0.03
-
in acute respiratory alkalosis for every decrease of pCO2 of 10mm pH increases by
0.08
-
in chronic respiratory alkalosis for every decrease of pCO2 of 10mm pH increases by
0.03
-
a pH which is too acid for the PCO2
metabolic acidosis
-
the only acid which can be exhaled via the lungs
carbon dioxide
-
includes all of the body's acids except carbon dioxide
metabolic acids
-
difference between the sum of the major anions and the major cations
anion gap
-
_____ is the same as Respiratory Acidosis
high pCO2
-
The normal value of pCO2 in arterial blood is __mmHg
40
-
implies a raised [H+] level with a normal PCO2
pure metabolic acidosis
-
high PCO2 causes molecules of CO2 and water to form carbonic acid which ionizes to increase both [HCO3-] and [H+]
pure respiratory acidosis
-
normal ph
7.4 (7.35-7.45)
-
-
-
-
__ refers to acid base disorders initiated by changes in PCO2
respiratory
-
__ refers to acid base disorders initiated by changes in HCO3
metabolic
-
a disorder with a low pH and a low bicarbonate concentration
metabolic acidosis
-
a disorder with a high pH and a high bicarbonate concentration
metabolic alkalosis
-
a disorder with a low pH and a high pCO2
respiratory acidosis
-
a disorder with a high pH and a low pCO2
respiratory alkalosis
-
what is a normal anion gap
7-13
-
what is the formula for anion gap
cations(Na+) - anions (Cl- + HCO3-)
-
anion gap metabolic acidosis is due to
gain in protons
-
non-anion gap metabolic acidosis is due to
loss of HCO3
-
how does the body compensate for metabolic acidosis
increased respiratory rate to blow off CO2
-
for every HCO3 fall by 1 mmol/L, pCO2 should fall by __mmHg
1.2
-
what is the differential for anion gap metabolic acidosis
- MUDPILES
- methanol,
- uremia,
- DKA,
- paraldehyde,
- INH,
- lactate,
- ethylene glycol,
- salicylates
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