-
High prevalence of __ deficits in hospitalized patients
nutritional
-
__ % of hospitalized patients suffer from some degree of malnutrition (depending on disease and population)
15 - 50
-
Loss of weight, appetite, muscle atrophy, and weakness in someone not trying to lose weight, usu. signifies an underlying disease
Cachexia
-
acute visceral protein depletion (chronic protein intake insufficiency), usually affects young children, edema, pigmentation, pot belly
Kwashiorkor
-
Simple starvation (chronic caloric intake insufficiency)loss of lean body mass, fat, and visceral proteins
Marasmus
-
40% in liver (rapidly depleted)
Glycogen stores
-
60% in muscle
Glycogen stores
-
Obligatory gluconeogenesis, Protein catabolism, Increased nitrogen loss, Unresponsive to glucose administration, Magnitude of loss proportional to injury
Adrenergic/Corticoid phase of Stressed Starvation (Surgery, Trauma)
-
__ common finding with deficiencies in niacin, thiamine, vitamin B6, vitamin B12
peripheral neuropathy
-
Represents the critical cellular mass necessary for cellular structure as well as function
lean body mass
-
Represents 40% of total body weight
lean body mass
-
Depletion is severe insult and defines patient morbidity and mortality
lean body mass
-
60% skeletal muscle
lean body cell mass
-
20% red blood cells and connective tissue
lean body cell mass
-
20% cell mass
lean body cell mass
-
Utilized for clinical determination of total body fat and skeletal muscle store. Simple, inexpensive, non-invasive technique
Anthropometric measures
-
__% of the total body protein is contained in skeletal muscle
60
-
this is major site of protein catabolism during starvation and/or illness
skeletal muscle
-
Most widely used biochemical marker of muscle mass
24-hr urine creatinine
-
Creatinine is degradation product of creatine,__
an energy storage compound located in skeletal muscle
-
Maintains plasma oncotic pressure and is a carrier for enzymes, drugs, hormones, etc.
Serum albumin
-
Serum albumin
Serum albumin
-
Carrier for iron. Limited use because level fluctuates with iron stores
Serum transferrin
-
Carrier for thyroxine and retinol-binding protein. Sensitive to acute changes in nutrient intake
Serum prealbumin
-
Resting energy expenditure calculated by using the __ equation
Harris-Benedict
-
Nitrogen Balance
N intake - N loss
-
Nitrogen Balance (N intake - N loss):If positive (goal +2 to +4), net state of __
anabolism
-
Nitrogen Balance (N intake - N loss): If negative, net state of __
catabolism
-
Nitrogen Intake (enteral and parenteral)(1 gm N/__ g Protein
6.25
-
Estimates severity of lean body mass catabolism and quantifies severity of metabolic stress
Catabolic Index (CI):
-
In general, adults will require nutritional support if NPO for greater than __ days
7
-
-
contraindications to enteral nutrition
gastroparesis, intestinal obstruction, ileus, high-output fistula, short bowel syndrome
-
Used for conscious patients; preferred for short-term feeding (< 30 days)
Nasoenteric Tube Feeding
-
Nasogastric: adequate gastric emptying require; maintain gastric residuals < __% of total infusion over prior 4 hours
50
-
Nasoenteric Tube Feeding: used in patients with high aspiration risk (neurological impairment; poor gastric motility)
Nasointestinal
-
tube feeds cause
diarrhea
-
in a patient with tube feeding and diarrhea check for __ before changing anything else
C. dif
-
Involves continuous infusion of hyperosmolar solution containing carbohydrates, proteins, fats, and other necessary nutrients through an indwelling catheter inserted into the superior vena cava
Total Parenteral Alimentation/Nutrition (TPN)
-
Any patient who will not have functioning GI tract for __ days should be considered for TPN
5-7
-
Principal indication for __ are found in seriously ill patients suffering from malnutrition, sepsis, or surgical or accidental trauma when use of the GI tract for feedings is not possible
parenteral alimentation
-
1. Intravenous vitamin preparations should be added 2. Vitamin K and folate should be administered once a week 3. Vitamin B12 is given once a month intramuscularly
Parenteral Alimentation
-
May present as dry, scaly dermatitis and loss of hair - Syndrome may be prevented by periodic infusion of a fat emulsion equal to 4 - 5% of total calories
Essential Fatty Acid Deficiency
-
- Most frequent trace mineral deficiency is __, which presents as an eczematoid rash developing both diffusely and at intertriginous areas
zinc
|
|