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Energy to power muscles contractions is released when oxygen combines with chemical compounds (carbohydrates, fats, proteins) in the cell.
ATP (Adenosine Triphosphate)
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Primary energy source for short, maximum performance events (i.e. sprints, cycling).
Carbohydrates
-
Energy source for the cell, being important for endurance events.
Fats
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Maintain and repair body tissues and are not normally used as an energy source to power muscle activity.
Proteins
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What are the two limiting factors in cellular energy production?
- Enough oxygen
- Availability of appropriate fuel (carbohydrates (fats and proteins can be used but carbohydrates are better)
-
Controlled oxidation in the cell is accomplished by "refining" these three basic compounds (carbohydrates, fats, and proteins), to what single common chemical compound?
ATP
-
A pathway for production of ATP.
A high energy molecule found in all muscle cells.
Great for "running for the bus" - emergency use
Not the best for sprint activities.
Phosphocreatine
-
A pathway for production of ATP.
Requires oxygen.
Can produce ATP from carbohydrates, fats, and protein.
Good for endurance activities.
Aerobic metabolism
-
A pathway of production of ATP.
Occurs in the absence of oxygen and limited to carbohydrates (glucose or glycogen) as a fuel source at the cost of lactic acid buildup in muscle (pain).
Generally the source of energy only for short bursts of high level activity lasting several minutes at most (sprints).
Glycolysis or anaerobic metabolism
-
When there is a cell receptor problem what can occur?
Cholesterol and diabetes problems
-
-ate
acids with COOH group
-
What process only happens in the Liver.
Gluconeogenesis
-
What is the major form of stored carbohydrate in animals?
Glycogen
-
What is the major form of stored carbohydrate in plant cells?
It is also the major source of dietary carbohydrates for humans.
Starch
-
Digestion in the gut converts all carbohydrates to this?
Monosaccharides
-
What is the livers central role concerning dietary glucose?
Storage and distribution within the body of all fuels
-
In what form is the fuel stored as in the Liver?
Glycogen
-
What does the liver convert fuel to?
Where is it stored and what what form is it in?
- Fatty Acids
- Stored in adipose tissue in the form of triglycerides
-
Where do all nutrients pass thru?
Hepatic portal vein - functions as an artery
-
What two major areas store Glycogen?
-
What is the term for converting glycogen to glucose?
Glycogenolysis
-
Can muscles release glucose to circulatory system?
No
-
Why do muscless store more glycogen than the Liver?
There is more muscle mass that there is Liver.
-
Where is glucose 6-phosphatase found?
Only in the Liver
-
The breaking down of glucose.
The process of splitting a 6-carbon chain (C6H12O6) into two- 3-carbon chains called pyruvate (C3H6O3)
Glycolysis
-
Pyruvate is reduced to a compound called Lactate in the process called?
Anaerobic Glycolysis
-
Pyruvate is transported inside mitochondria and oxidized to a compund called?
Acetyl Coenzyme A (aceytl CoA) by the process of Aerobic Glycolysis
-
The Tricarboxylic Acid Cycle or Citric Acid Cycle is also know as?
Krebs Cycle
-
Cycling of lactate produced by red blood cells and muscle during anaerobic respiration back into glucose
Cori Cycle
-
This hormones source is the pancreas and targets Liver tissue
Glucagon - stimulates glycogen breakdown
-
This hormones source is the Adrenals and targets muscle
Adrenaline - stimulates glycogen breakdown
-
Which organ in the body is most sensitive to glucose levles?
Brain
-
Small islands of endocrine cells in the pancreas
pancreatic islets
-
This hormone targets Liver, Fat, and Muscle cells
Insulin
-
Stimulates the liver and muscles to break down stored glycogen (glycogenolysis) and releases glucose
Stimulates gluconeogenesis in the liver and kidneys
Glucagon
-
Juvenile Diabetes
Insulin-dependent type
Cannot produce insulin naturally due to β-cells being destoryed
Type 1 Diabetes
-
Adult-onset diabetes
Non-insulin-dependent diabetes
Has higher than normal insulin in the blood but does not accept Insulin
Type 2 Diabetes
-
Similar to Type 2 diabetes but found in pregnant women
Gestational diabetes
-
Medical term for: Excessive thirst
Polydipsia
-
Medical term for: Frequent urination
Polyuria
-
Medical term for: Extreme hunger or constant eating
Polyphagia
-
Medical terms for: Presence of glucose in the urine
Glycosuria
-
Metabolism of fatty acids leads to the production of acidic ketones in the blood
Ketoacidosis
-
Glyceraldehyde
Dihydroxyacetone
Examples of 3 Carbon Triose
-
Erythrose
Example of 4 carbon Tetrose
-
Ribose
Ribulose
Xylulose
Example of 5 carbon Pentose
-
Glucose
Galactose
Mannose
Fructose
Example of 6 carbon Hexose
-
Contains carboxylic acid group and ketone group. A weak acid that can break down into acetone and carbon dioxide
Acetoacetic Acid
-
An example of a ketone, naturally produced in the body as a product of the metabolic process
Acetone
-
Increased acidity in the blood plasma
Acidosis
-
Self-digestion, lysomes release digestive enzymes into the cytoplasm causing the cell to "eat" itself
Autolysis
-
Found in pancreatic islets which secrete glucagon to regulate glucose in the blood
α-cell
-
Found in pancreatic islets which secrete insulin to regulate glucose in the blood
β-cell
-
Found in the blood, linked to β-cell functionality
C-peptide
-
Urine Production
Diuresis
-
Hormone secreted by the pancreas, raises blood glucose levels
Glucagon
-
Glycogen Synthesis
Glycogenesis
-
Converting glycogen to glucose
Glycogenolysis
-
Glucose in the urine
Glycosuria
-
Maintaining equilibrium within the body
Homeostasis
-
High Blood Sugar (higher than normal)
Hyperglycemia
-
Low Blood Sugar (lower than normal)
Hypoglycemia
-
IDDM
Insulin-Dependent Diabetes Mellitus (Type 1 Diabetes)
-
Regulates glucose levels in the blood
Insulin
-
metabolic state associated with high concentration of ketone bodies, formed by the breakdown of fatty acids and deamination of amino acids
Ketoacidosis
-
The breakdown of fatty acids to energy used by kidney and liver
Ketone bodies
-
Elevated levels of ketone bodies in the body
Ketosis
-
The breakdown of lipids
Lipolysis
-
NIDDM
Non-Insulin-Dependent Diabetes Mellitus (Type 2 Diabetes)
-
Increased urination caused by the presence of certain substances (such as glucose) in the small tubes of the kidneys
Osmotic Diuresis
-
Polydipsia
Excessive Thirst
-
-
Polyuria
Excessive or abnormal urination
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