Compounding: Look Alike Sound Alike and FDA indications

  1. Accolate
    • zafirlukast
    • prophylaxis andd chronic treatment of asthma
    • leukotriene inhibitor
    • 20mg BID
    • 10mg, 20mg
  2. Aclovate
    • alclometasone
    • treatment of inflammation of corticosteroid responsive dermatosis
    • adrenal glucocorticoid
    • topical 2-3x daily
  3. counselings for Accolate vs. Aclovate
    • Accolate: take on empty stomach, 1h before or 2h after meal
    • Aclovate: avoid sunlight
  4. Advicor
    • niacin/lovastatin
    • lovastatin: treatment of primary hypercholesterolemia
    • ER niacin: adjuctive treatment of dyslipidemia to lower the risk of recurrent MI and/or slw progression of coronary artery disease
    • 500mg niacin/20mg lovastatin qd (max 2000mg/40mg)
  5. Altocor
    • lovastatin
    • adjuctive to dietary therapy to decrease elevated serum total and LDL cholesterol concentrations in primary hypercholesterolemia
  6. counseling points for Advicor vs. Altocor
    Advicor: category X, may cause flushing, take with low fat snack

    Altocor: category X, take with food, take at bedtime
  7. Avelox
    • moxifloxacin
    • acute sinusitis caused by S. pneumoniae, H. influenza, or M. catarrhalis
    • 400mg IV/PO daily for 10 days
    • IV 400mg/250ml, 400mg tab, ophthalmic soln
  8. Avonex
    • interferon beta 1a
    • treatment of relapsing forms of MS
    • 30mcg IM once weekly
  9. counseling points for Avelox vs. Avonex
    • Avelox: d/c if rash develops, drink 8oz of water after each dose, avoid antacid, sucralfate, iron or MV containing Zn within 2 hrs of dose, may cause dizziness
    • Avonex: may cause drowsiness, dizziness, nausea, HA, keep hydrated unless otherwise instructed, notify MD immediately of suicidal ideation
  10. Clinoril
    • sulindac
    • osteoarthritis, rheumatoid arthritis, ankylosing spondylitis
    • NSAID
    • 150mg, 200mg tabs
  11. Clozaril
    • clozapine
    • management of severely ill schizophrenic patients who fail to respond adequately to standard antipsychotic drug treatment
    • 25, 50, 100, 200mg tab
  12. counseling points for Clinoril vs. Clozaril
    Clinoril: may take 2 wk to see results, may cause drowsiness, take with food/milk if GI upset, avoid alcohol, avoid aspirin or aspirin-containing product

    Clozaril: weekly WBC count, may cause seizures and orthostatic hypotension
  13. DiaJect vs. Diastat
    • both for treatment of convulsive disorders
    • Diastat: set patient's dose prior to dispensing
  14. Hydroxyzine
    • HCl: Atarax
    • pamoate: Vistaril
    • treatment of anxiety
    • 50-100mg po QID
  15. Hydralazine
    • Apresoline
    • management of moderate to severe hypertension, congestive heart failure, hypertension secondary to pre-eclampsia/eclampsia
  16. counseling points for hydroxyzine vs. hydralazine
    hydroxyzine: may cause drowsiness, avoid alcohol, breast feeding is contraindicated

    hydralazine: take with meal, avoid alcohol, report wt gain >5 lbs/wk or swelling of ankles, may cause postural hypotension, dizziness, NV
  17. Lamisil
    • terbinafine
    • oral treatment of onychomycosis of the toenail or fingernail due to dermatophytes
  18. Lamictal
    • lamotrigine
    • adjuctive therapy in pediatric and adult patients with partial seizures or generalized seizures for Lennox-Gastaut syndrome
  19. counseling points for Lamisil vs. Lamictal
    • Lamisil: hypersensitivity or drowsiness may occur
    • Lamictal: take tablet with food to avoid GI upset, notify MD if rash or liver dysfunction develops
  20. Lasix
    • furosemide
    • treatment of edema associated CHF, cirrhosis of the liver and renal disease
  21. Lidex
    • fluocinonide
    • anti-inflammatory, antipruritic
  22. counseling points for Lasix vs. Lidex
    Lasix: take with food/milk if GI upset, take in AM, avoid sunlight, may cause orthostatic hypotension

    Lidex: external use only, avoid excessive sunlight
  23. Levaquin
    • levofloxacin
    • community acquired pnemonia, acute bacterial exacerbation of chronic bronchitis caused by susceptible strains of microorganims
  24. Levsin SL
    • hyoscyamine
    • adjunctive therapy in tx of peptic ulcer, irritable bowel syndrome, neurogenic bladder or bowel disorders, biliary or renal colic and other gastric hyperspasmodic or hypersecretory disorders
  25. counseling points for Levaquin vs. Levsin
    Levaquin: d/c if rash develops, drink 8oz of water after each dose, no antacid, sucralfate, iron, MV with Zn within 2 hrs of dose, avoid sunlight, monitor BG if taking anti-diabetic meds, d/c if hypoglycemia (contact MD)

    Levsin: take in empty stomach, no antacid, avoid hot weather, may cause drowsiness
  26. Lotronex
    • alosetron
    • treatment of women with severe diarrhea-predominant irritable bowel syndrome who have failed to respond to conventional therapy
    • serotonin receptor antagonist 5-HT3
  27. Lotrimin
    • clotrimazole
    • treatment of tinea corporis (body ringworm), tinea cruris, and tinea pedis caused by Epidermophyton floccosum, Microsporum canis, Trichophyton mentagrophytes or T. rubrum
  28. counseling points for Lotronex vs. Lotrimin
    Lotronex: [BBW] d/c immediately in patients with constipation. acute ischemic colitis has been reported during treatment. patient must read and sign a "patient-physician" agreement before receiving the initial prescription; absorption reduced with food

    Lotrimin: complete full course of therapy
  29. Myoflex
    • trolamine salicylate
    • relief of muscular aches, rheumatism, neuralgia, sprains, arthritis on intact skin
  30. Mycelex
    • clotrimazole
    • treatment of susceptible fungal infection (oropharyngeal candidiasis, dermatophytoses, superficial mycoses, cutaneous candidiasis, vulvovaginal candidiasis)
  31. counseling points for Myoflex vs. Mycelex
    Myoflex: external use only

    Mycelex: troche: allow to dissolve slowly over 15-30min
  32. Plavix
    • clopidogrel
    • reduction of atherosclerotic events in patients with atherosclerosis documented by recent stroke, recent MI or established peripheral arterial disease
  33. Paxil
    • paroxetine
    • treatment of depression and OCD
  34. counseling points for Plavix vs. Paxil
    Plavix: contact MD if symptoms of infection; increased bleeding time

    Paxil: may take up to 2 wk to see results, may cause drowsiness, avoid alcohol, contact MD if swelling or excessive thirst
  35. Plendil
    • felodipine
    • for the treatment of hyhpternsion with or without a thiazide diuretic
  36. Isordil
    • isosorbide dinitrate
    • prevention and treatment of angina pectoris
  37. counseling points for Plendil vs. Isordil
    Plendil: avoid grapefruit juice, practice good dental hygiene

    Isordil: do not crush or chew SR capsules, swallow whole with 8 oz water, avoid excesive alcohol, combination may cause severe hypotension, if chest pain, seek immediate emergency medical help
  38. quinine
  39. quinidine
    prophylaxis after cardioversion of A.fib and/or A. flutter to maintain normal sinus rhythm
  40. counseling points for quinine vs. quinidine
    quinine: preg X, notify MD if cinchonism (tinnitus, distubed vision, dizziness, HA, confusion, hearing loss)

    quinidine: do not take with grapefruit juice, caution while driving if dizzy/drowsy/visual change
  41. selegiline
    adjunct in the management of parkinson's disease in which levodopa/carbidopa is deteriorating
  42. Salagen
    • pilocarpine hydrochloride
    • symptomatic treatment of xerostomia caused by salivary gland hypofunction resulting from radiotherapy for cancer of the head and neck or Sjogren's syndrome
  43. counseling points for selegiline vs. Salagen
    selegiline: take with meals if GI upset, avoid tyramine containing food, maintain adequate hydration, avoid alcohol, may cause drowsiness, dizzy, confusion, orthostatic hypotension, constipation

    Salagen: avoid high fat meal
  44. Serzone
    • nefazodone
    • treatment of depression
  45. Seroquel
    • quetiapine
    • for the management of manifestation of psychotic disorders
  46. counseling for Serzone vs. Seroquel
    Serzone: may take 2-3 wk to achieve desired results, avoid alcohol, report persistent insomnia or excessive daytime sedation, inform MD immediately of suicidal ideation

    Seroquel: may have drowsiness, use caution when rising, do not change dosage except MD order
  47. Sertraline
    • zoloft
    • treatment of depression and OCD
  48. Soriatane
    • acitretin
    • treatment of severe psoriasis
  49. counseling points for Sertraline vs. Soriatane
    Sertraline (Zoloft): continued tx may be needed to see improvement; avoid alcohol, use caution when performing tasks that require alertness, do not abruptly d/c

    Soriatane: pregnancy X, hepatotoxicity warning, take with food, avoid vitamin A product, alcohol contraindicated
  50. Tamoxifen
    palliative or adjunctive treatment of advanced breast cancer
  51. tamsulosin
    treatment ofo signs and symptoms of benign prostatic hyperplasia (BPH)
  52. counseling points for tamoxifen vs. tamsulosin
    tamoxifen: annual ophthalmic exam, gynecological exam and mammogram if using for long term, may cause hot flash, hair loss and loss of libido, bone pain may indicate a good therapeutic response

    tamsulosin: once daily, 30 min after same meal each day, may cause drowsiness, postural hypotension
  53. Topamax
    • topiramate
    • adjunctive therapy in pediatric (2-1yo) and adult patients with partial onset seizureor primary generalized tonic-clonic seizures and in patients 2 yr and older with seizures associated with Lennox Gastaut syndrome.
  54. Toprol XL
    • metoprolol succinate
    • management of hypertension
  55. counseling points for Topamax vs. Toprol XL
    topamax: may cause drowsiness, avoid alcohol, contact MD if eye pain or blurred vision, keep hydrated

    Toprol: take with food, do not crush or chew, may cause dizziness, masking of hypoglycemic symptoms in diabetics
  56. Vicodin
    • APAP and hydrocodone
    • relief of moderate to moderately severe pain
  57. Visicol
    • sodium phosphate
    • short term treamtent of constipation and to evacuate the colon for rectal and bowel exam
  58. counseling points for Vicodin vs. Visicol
    Vicodin: may cause drowsiness, avoid alcohol, may take with food or mild to avoid GI upset (warning: may be habit forming, CIII)

    Visicol: may cause diarrhea, excessive prolonged use as a laxative may cause dependence
  59. Zantac
    • ranitidine
    • short term treatment of active duodenal ulcer
  60. Zestril
    • lisinopril
    • treatment of hypertension
  61. counseling points for Zantac vs. Zestril
    Zantac: take food/milk if GI upset

    Zestril: avoid salt substitute containing potassium, contact MD if swelling occurs
  62. Zebeta
    • bisoprolol
    • treatment of hypertension, alone or in combination with other agents
  63. Zetia
    • ezetimibe
    • for the adjunct therapy to diet for the reduction of elevated total C, LDL C and ApoB in patients with primary (familial and non familial) hypercholesterolemia
  64. counseling points for Zebeta vs. Zetia
    Zebeta: do not take with antacids, diabetics monitor BG, report unresolved swelling of extremities

    Zetia: do not take within 2 hr before or 4 hr after bile acid sequestrant (cholestyramine), follow prescribed diet, contact MD if myopathy symptoms occurs especially if also on HMG-CoA reductase inhibitor (statin)
  65. Zyrtec
    • cetirizine
    • relief of symptoms associated with seasonal allergic rhinitis due to allergens such as ragweed, grass and tree pollens in adults and children over 2 yrs
  66. counseling points for Zestril vs. Zyrtec
    Zestril: avoid salt substitutes containing potassium, contact MD if swelling occurs

    Zyrtec: may cause drowsiness, avoid alcohol, skip dos if >6 hrs late and return to normal schedule, do not double dose
  67. counseling points for Zyrtec vs. Zantac
    Zyrtec: may cause drowsiness, avoid alcohol, skip dose if >6 hours passed and return to normal schedule, do not double dose

    Zantac: take food/milk if GI upset
  68. Zyprexa
    • olanzapine
    • for the management of the manifestations of psychotic disorders
  69. counseling points for Zyrtec vs. Zyprexa
    zyrtec: may cause drowsiness, avoid alcohol, skip dose if >6 hr passed and return to normal schedule, do not double dose

    Zyprexa: may cause drowsiness, use caution when rising, do not change dosage except on orders of MD, use ZYDIS immediately after opening foil sachet
Card Set
Compounding: Look Alike Sound Alike and FDA indications
Compounding: Look Alike Sound Alike