Neutropenic Fever

definition of a fever
- single oral of 101
- greater than 100.4 for more than 1 hour
How to calculate ANC

ANC = WBC x % Neutrophils

%Neutrophils = %bands + % segs
At onset of signs and symptoms of infection, what should be done with afebrile patients?

started on empiric therapy
High risk of infection
- Prolonged neutropenia (>7 days)
- Uncontrolled malignancy
- Hypotension
- Complex infection
- Significant comorbidities
If patient remain febril through the first 5-7 days, what should be initiated

antifungal drug with or without antibiotic change
48 hours after afebrile and ANC greater than 500

stop antibiotics
If ANC is less than 500 by 7, initial low risk, clinically well, antibiotics can be stopped when?

the patient is afebrial for 5-7 days
If ANC < 500 by day 7, initial high risk (<100, mucositis, unstable signs)

continue anitibiotics
if persistent fever and ANC > 500

stop 4-5 days after ANC > 500
if persistent fever and ANC < 500

continue for 2 weeks

Author

Anonymous

8589

Card Set

Neutropenic Fever

Description

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Updated

2010-03-01T07:16:42Z