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Synthesis of Ethers

  1. Williamson Ether Synthesis
    R-OH NaH-> R-O- primary alkyl halide-> R-O-R
  2. R-OH NaH->
    R-O-
  3. R-O- R-OH + TsCl, pyridine->
    R-O-R
  4. Alkoxy Mercuration
    R-CH=CH-R 1) Hg(OAc)2, R-OH 2) NaBH4-> R-O-R
  5. R-OH heat, H2SO4->
    R-O-R
  6. R-O- --> R-O-R (Williamson Ether Synthesis)
    primary alkyl halide
  7. R-CH=CH-R --> R-O-R (alkoxy mercuration)
    • 1) Hg(OAc)2, R-OH
    • 2) NaBH4
Author
enger91
ID
85214
Card Set
Synthesis of Ethers
Description
University of MN twin cities, CHEM 2302
Updated

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