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-the scientific study of life
biology
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-substances that cannot be broken down into other substances
-92 naturally occurring elements on Earth
elements
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-occur in smaller amounts
-are essential for life
trace elements
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-a chemical compound that releases H+ to solution
-0-7 on pH scale
acid
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-a compound that accepts H+ and removes it from a solution
-7-14 on pH scale
base
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-substances that resist change in pH
buffers
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-carbohydrates
-proteins
-nucleic acids
-not lipids
macromolecules
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-links two monomers together
-removes a molecule of water
dehydration reaction
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-breaks bonds between monomers
-adds a molecule of water
-reverses the dehydration reaction
hydrolysis
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-sugars or sugar polymers
-include small sugar molecules in soft drinks
-long starch molecules in pasta and potatoes
carbohydrates
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-simple sugars that cannot be broken down by hydrolysis into smaller sugars
-build carbs
monosaccharides
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-a double sugar
-constructed from two monosaccharides
-formed by a dehydration reaction
disaccharides
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-complex carbohydrates
-made of long chains of sugar units and polymers of monosaccharides
polysaccharides
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-neither macromolecules nor polymers
-Hydrophobic, unable to mix with water
lipids
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-a key component of cell membranes
-the “base steroid” from which your body produces other steroids, such as estrogen and testosterone
cholesterol
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-polymers constructed form amino acid monomers
-perform most of the tasks the body needs to function
-form enzymes
proteins
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-chemicals that change the rate of a chemical reaction without being changed in the process
enzymes
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-specific sequence of amino acids in a protein
primary structure of proteins
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-pleated sheet/alpha and beta helix
secondary structure of proteins
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-polypeptide
Tertiary Structure of Proteins
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-protein with four polypeptides
quaternary structure of proteins
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-a specific stretch of DNA that programs the amino acid sequence of a polypeptide
gene
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-bacteria and archaea
prokaryotic cells
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-plants, fungi and animals
-only cells that have organelles
eukaryotic cells
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-tiny structures that build proteins
ribosomes
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-membrane-bound structures that perform specific functions
-most important is the nucleus
organelles
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-fibers formed by long DNA molecules and associated proteins that are stored in the nucleus
chromatin
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-each long chromatin fiber
chromosome
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-organelles that perform photosynthesis
chloroplast
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-the sites of cellular respiration, which produce ATP from the energy of food molecules
mitochondria
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-the total of all chemical reactions in an organism
-most reactions require assistance of enzymes
metabolism
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-products of a reaction inhibit the enzyme required for its production
-prevents the cell from wasting resources
feedback regulation
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-has a higher concentration of solute
hypertonic
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-has a lower concentration of solute
hypotonic
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-does not require the use of oxygen
anaerobic
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-can produce up to 38 ATP molecules for each glucose molecule consumed
cellular respiration
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glycolysis
- -a 6C glucose molecule is split in half to form two 3C molecules, or 2 molecules of pyruvic acid
- -produces a net of two molecules of ATP per glucose molecule
- -does not require oxygen
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-the anaerobic harvest of food energy
-relies on glycolysis to produce ATP
-able to sustain many types of microorganisms
fermentation
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-used by plants, some protists and some bacteria
-transforms light energy into chemical energy
-uses carbon dioxide and water as starting materials
-the reactants are the waste products of cellular respiration
-sunlight provides the energy
-glucose and oxygen are produced
photosynthesis
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-convert solar energy to chemical energy
-two types of photosystems: water-splitting and NADPH-producing
-located in the thylakoid membrane
light reactions
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-uses the products of the light reactions to make sugar from carbon dioxide
-functions like a sugar factory within the stroma of a chloroplast
-regenerates the starting material with each turn
calvin cycle
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-the orderly sequence of events that extend from the time a cell is first formed from a dividing parent cell to its own division into two cells
cell cycle
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-most of a cell cycle is spent in this phase
-doubles everything in its cytoplasm
-grows in size
interphase
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-chromatin fibers coil
-each chromosome has two identical sister chromatids
prophase
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-begins when sister chromatids separate
-each chromosome daughter is now its own full fledged chromosome
anaphase
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-mitotic spindle is now fully formed
-chromosomes are in the middle of the cell
-pulls chromosomes
metaphase
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-happens during telophase
-divides the cytoplasm
-different in plant and animal cells
telophase (cytokinesis)
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-where the nucleus and its contents divide evenly into two daughter nuclei
mitosis
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-sexual reproduction
meiosis
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-make up DNA and RNA
-joined by a sugar-phosphate backbone
-nitrogenous bases found in DNA: T, C, A, and G (in RNA, U instead of T)
nucleotides
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DNA backbone
- -deoxyribose sugars
- -phosphate groups
- -nitrogenous bases
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-like a rope ladder twisted into a spiral
-ropes at the sides represent the sugar-phosphate backbone
-each rung represents a pair of bases connected by hydrogen bonds
DNA strand
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-organism's genetic makeup
-what is supposed to be there
genotype
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-organism’s physical traits
-what can be seen of an organism
phenotype
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-DNA to RNA
transcription
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-RNA into protein
-the conversion from the nucleic acid language to the protein language
-requires: mRNA, ATP, enzymes, ribosomes, tRNA
translation
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-a nucleotide sequence with a “start transcribing” signal
promoter
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initiation of transcription
- -first phase of transcription
- -RNA polymerase attaches to the promoter
- -RNA synthesis begins
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elongation of transcription
- -second phase of transcription
- -RNA grows longer
- -RNA strand peels away from the DNA template
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termination of transcription
- -third phase of transcription
- -RNA polymerase reaches terminator
- -polymerase detaches from the RNA
- -the DNA strands rejoin
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-sequence of DNA bases with a "strop transcribing" signal
terminator
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-adding a 5 prime cap and poly A tail
-removing introns
-splicing exons together to form messenger RNA
RNA processing
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-any change in the nucleotide sequence of DNA
-can change the amino acids in a protein
mutation
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-are not cellular
-cannot reproduce on their own
viruses
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-misfolded proteins
prions
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-the study of the structure of an organism
anatomy
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-the study of the function of an organism’s structural equipment
physiology
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-an integrated group of similar cells that perform a specific function
tissue
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-covers the surface of the body
-lines organs and cavities within the body
epithelial tissue
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-may be liquid, jellylike or solid
connective tissue
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-the most widespread connective tissue
-binds epithelia to underlying tissue
-holds organs in place
loose connective tissue
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-stores fat
-stockpiles energy
-pads and insulates the body
adipose tissue
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-a connective tissue with a matrix of liquid
-contains red and white blood cells suspended in plasma
blood
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-has a dense matrix of collagen
-forms tendons and ligaments
fibrous connective tissue
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-has a strong rubbery matrix
-functions as a flexible, boneless skeleton
-forms the shock-absorbing pads that cushion the vertebrae of the spinal column
cartilage
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-a rigid connective tissue
-has a matrix of collagen fibers hardened with deposits of calcium salts
bone
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-consists of bundles of long, thin, cylindrical cells
-has specialized proteins that contract when stimulated by a nerve
muscle tissue
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-attached to bones by tissue
-responsible for voluntary movements
-striated because the contractile apparatus forms a banded pattern in each cell or fiber
skeletal muscle
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-composed of cells that are branched and striated
-found only in heart tissue
-responsible for the contraction of the heart
cardiac muscle
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-named for its lack of obvious striations
-found in the walls of various organs
-involuntary
smooth muscle
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-makes communication of sensory information possible
-is found in the brain and spinal cord
-consists of a network of neurons
nervous tissue
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-consists of two or more tissues packaged into one working unit that performs a specific function
organ
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-the body’s tendency to maintain relatively steady conditions in the internal environment when the external environment changes
homeostasis
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-most mechanisms of homeostasis depend on this common principle
-results of a process inhibit the same process
-like when a thermostat turns off a heater when room temperature rises to a set point
negative feedback
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-the results of a process intensify that same process
-uterine contractions during childbirth
positive feedback
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-mainly feed on plants
herbivores
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eat plants and animals
omnivores
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-the breakdown of food to small nutrient molecules
digestion
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-the uptake of the small nutrient molecules by cells lining the digestive tract
absorption
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-begins the process of digestion
-involves physical processes like chewing
-begins in the mouth
mechanical digestion
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-the chemical breakdown of food by digestive enzymes
-begins in the mouth
-most occurs in the duodenum, the first part of the small intestine
chemical digestion
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-the longest part of the alimentary canal
-the major organ for chemical digestion and absorption of nutrients into the bloodstream
small intestine
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-shorter, but wider, than the small intestine
-about 1.5 meters in length
-absorbs water
large intestine
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-receives blood in the heart
atrium
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-part of the heart that pumps blood away from the heart
ventricle
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-carry blood away from the heart
arteries
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-the site of exchange between blood and interstitial fluid
capillaries
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-return blood back to the heart
veins
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blood path
- Right atrium
- Right ventricle
- Pulmonary artery
- Capillaries of lung
- Pulmonary vein
- Left atrium
- Left ventricle
- Aorta
- Capillaries of head, chest and arms
- Superior vena cava
- Inferior vena cava
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-sets the tempo of the heartbeat
SA node
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-cells that carry oxygen
red blood cells
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-cells that fight infection
white blood cells
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-aid blood clotting
platelets
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