Pharm Final Review

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Analeptic-

CNS stimulent used to reverse drug-induced CNS depression, particularly Respiratory depression
What receptors does Strychnine act on?

Glycine Antagonist
How does phenobarb work?
- GABA mediated inhibition
- Inhibits glutamate activity
- Reduces Ca fluxes across mem
*Weak bronchodilators include:
- Theophylline
- Aminophylline
Which seizure medication is not used in cats?

Br
What medication can cause acute hepatic necrosis in cats?

Diazapam
Steady State of Phenobarb is mantained w/in...

14-16 days
Weak bronchiodilators are used to Tx
- Asthma (bronchodilator in dogs, cats & horses)
- Cong Heart Dz (dilates coronary aa)
What anticonvulsant causes blood dyscrasis and ALT/ALP

Pehnobarb
What drug => PEMA?

Primidone
What drug is not used in cats, and not encouraged for used in dogs D/T hepatotoxic Fx?

Primidone
Antihistaminic Actions:

Relaxation of contracted bronchiolar smooth m*
Which type of seizure is most common in dogs?

Generalized tonic-clonic (Grand-Mal)
Status Epilepticus-

When P fails to recover btw repeated tonic-clonic seizures, lasting for >30 mins
What drugs has antithrombic and anticoagulatory actions?

Heparine
Heparine binds to ___ => ___ => ____
- Antithrombin III factor
- Conformational Change
- Inhibits thrombin & Activates factor Xa
What does Heparine increase?
- Factor Xa
- Plasminogen Activator
- Tissue Activating Factor
What drug can be used to antagonise heparine-induced hemorrhagic action?

Protamine Sulfate
What drug can be used to treat thromboemboli?

Heparin
What drug activates purinergic receptors?

Ticlopidine
What drug selectively acts on plasminogen in fibrin clots?

Tissue Plasminogen Activator
What anabolic steroid is used in horses?

Boldenone undecyclenate (Equipoise)
Anabolic Steroids are designated as Class ___

III
NSAIDS are ____ (acid/base properties)

Weak acids
Three therapeutic Fx of NSAIDS:
- Antipyretic
- Analgesic
- Anti-inflammatory
Active metabolite of phenylbutazone:

oxyphenbutazone
Active metabolite of asprine:

salycyclic acid
What drug is a strong inhibitor of COX and inhibits lipooxygenase?

Ketoprofen
Uses of acetominophen:
- Analgesic
- Antipyretic
Acetominophen is excreted as ...

Glucuronic Acid Derivitive
What drug is used to reduce inflammation of the CNS?

Acetominophen (Paracetamol)

Author

HLW

85047

Card Set

Pharm Final Review

Description

Pharm Final Review

Updated

2011-05-10T18:55:45Z

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