-
What does Hemoglobin do?
- – The essential oxygen carrier of the blood
- – A protein used by RBC’s to distribute oxygen to other tissues and cells in the body
-
What are the Lab value ranges for Hemoglobin?
- Remember "15" as a normal value
- Ranges Adult
- Male 14.0 - 17.4 g/dl
- Female 12.0 -16.0 g/dl
- Pediatric 11.0 - 16.0 g/dl
- Neonate 10.7 – 17.1 g/dl
-
What does Hematocrit do?
- – The percentage of red blood cells (RBC) in a volume of whole blood
- – Refers to the amount of blood that is occupied by RBC’s
- • It’s like chocolate milk: how much of it is chocolate and how much of it is milk
-
Normal Values for Hematocrit?
- (42)
- Ranges Adult
- Male 39% - 49%
- Female 34% - 44%
- Pediatric 32% - 45%
- Neonate 33% - 55%
-
Normal Range for WBC count
- – Adult 4,000 - 10,000 (cell/mcl) **
- – Pediatric 5,000 - 10,000 (cell/mcl)
-
Red Blood Cell Count
- Ranges Adult -5**
- Male 4.2- 5.6M/ul
- Female 3.8– 5.1M/ul
- Pediatric 3.5– 5.0M/ul
- Neonate 3.3– 5.5M/ul
-
What are Neutorphils?
- • Main defender of the body against
- – Infection
- – Antigens
- • High levels may indicate an active infection
-
Normal Neutorphil values
- • Should account for anywhere between 38% and 80% of the WBC count
- • Ranges
- Adult 50% - 75% **
- Pediatric 30% - 60%
-
BASOPHILS
- High levels are found in allergic reactions
- • Ranges 0% - 1%
-
EOSINOPHILS
- Produces the anti-inflammatory protein histamine
- Ranges 1% - 5%
-
Lymphocytes
- Bear the major responsibility for carrying out the activity of the immune system
- Adult 15% - 40%
-
Monocytes
- Responsible for removal of debris
- • Ranges 2% - 6%
-
Which Electrolytes are on a Chem 7 Blood screen?
- • Sodium
- • Potassium
- • Chloride
- • Bicarbonate
- • Magnesium
- • Phosphorus
- • Calcium
-
What role do Electrolytes have?
- • Involved in metabolic activities
- • Essential to the normal function of all cells
- • Positively and negatively charged molecules
- – Called ions
- • Intracellular
- • Extracellular(Interstitial)
- • In the bloodstream
- • In other fluids throughout the body
-
Which electrolytes are found more abundently inside of Cells?
- Potassium
- phosphate
- magnesium
-
Which electrolytes are found more abundently Outside of Cells?
Sodium and chloride
-
Normal Sodium (Na) levels
Ranges 135 - 145 mEq/L
-
What does Sodium do?
- The major extracellular cation and osmotically active solute
- • Major functions are
- –Water balance
- – Transmission of nerve impulses
- • Deficits lead to neurological changes
-
How is Sodum eliminated from the body?
-
What is Hypernatremia?
- Increased sodium level caused by
- • Water excess - Diuetics/ Diarrhea
- • Sodium loss
- – Manifestations
- • Confusions
- • Seizure
-
How do you treat Hypernatremia?
- • Diluting the sodium
- • Promoting excretion
- • Consider fluids (D5W)
- • Consider diuretics
- – Avoid rapid rehydration with hypotonic fluids
- • Can cause fluid shifts
-
What does Potassium (K) do?
- The principle cation in intracellular fluid
- Plays a crucial role in the formation of electrical impulses in nerves and muscle
-
What is considered in abnormally high Potassium levels?
- High level is above 5.0
- Broken cells would cause falsely elevate potassium levels
- – Referred to as hyperkalemia
- – DKA
- – Metabolic Acidosis
- – Uremia
- – Iatrogenic
- • Hemolysis
- It is considered severe over 8.0
- • Widening of the QRS complex
- • Bradycardia
- • Eventually, ventricular standstill
-
What is in a Potassium Cocktail?
- • Calcium Chloride – Acts as a cardiotonic
- • Sodium Bicarbonate- forces K back into the cells.
- • D50 – Counter acts the effect of Insulin
- • Insulin – Forces potassium back into the cell
- – Can also be given if the patient is showing signs of
- impending arrest
-
What is Hypokalemia?
Low serum potassium is referred to as hypokalemia and occurs when the serum potassium level falls below 3.5
-
How is Hypokalemia treated?
- • Treatment consists of replacing K+ with KCL.
- • NEVER push IV
-
Normal Potassium(K) ranges
Ranges 3.5- 5.0mEq/L
-
Chloride (Cl)
- A negatively charged ion found primarily in extracellular fluid.
- • Ranges 95 - 110mEq/L
-
Magnesium (Mag)- Causes of deficits
- Magnesium deficits MUST be corrected before it is possible to correct the potassium deficit.
- Diuretics, diarrhea and alcoholism are 3 very common causes of magnesium depletion.
- Over ½ of the total body stores are located in bone and less than 1% is in plasma.
-
Complications of hypermagnesemia are
Complete heart block can be seen at serum levels of 7.5 mEq/L and respiratory depression and coma can occur at serum levels of 10mEq/L.
-
Normal Magnesium range is
1.3– 2.2 mEq/L
-
Normal Bicarb levels
22- 26 mEq/L
-
What is Anion Gap
- The equivalence of cations in a solution always balances the equivalents of anions.
- [Na + K] - [Cl + HCO3] = anion gap
-
Normal values for the Anion Gap are
- < 12
- (>12 is Metabolic Acidosis)
-
Glucose Range
60- 120 mg/dl
-
Blood Urea Nitrogen (BUN)
- • Ranges 10- 20 mg/dl
- – Elevated
- • Renal Failure
- • Dehydration
- • GI Bleed
- •Low- Protein deficiency
-
Creatinine
- The most important indicator of glomerular filtration rate and is a by/product of normal muscle metabolism.
- Ranges 0.6mg/dl – 1.2mg/dl
-
Cardiac Enzymes (CK/MB values)
- CK Adult Male 96– 140U/L
- MB Adult Male 0% - 5 %
-
Troponin
- • Troponin I < .01
- • Troponin T < .01
-
Myoglobin (MYO)
- intracellular storage site for oxygen.
- • Ranges Male < 90ng/ml
-
B-type natriuretic peptide (BNP)
- Commonly used to assisst in the diagnosis and monitoring of Congestive Heart Failure
- Normal value: < 100
-
Prothrombin Time (PT)
- • The PT is used to monitor Coumadin therapy.
- • Ranges 11 sec - 13 sec
-
Partial Thromboplastin Time (PTT)
- • The PTT is used to monitor heparin therapy
- Ranges 30 sec – 45 sec
-
Platelets (PLT)
- Ranges 130 – 400 k/mcl
- Thrombocytopenia is the term used for a low platelet count.
|
|