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14-Movement
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Name one hypokinetic disorder
Parkinson's disease
Name some hyperkinetic disorders
Huntington's
Hemiballismus
Athetosis
What is the age of onset for Parkinson's disease
40-70 y/o
Which movement condition is the most multi-factorial and idiopathic?
Parkinson's disease
What are some other causes for Parkinson's disease?
Maganese
Intoxication
Drugs-
Neuroleptics
Multiple cerebral
infarcts
Swine Flue
What are some clincal features of Parkinson's disease?
Bradykinesia
cogwheel rigidity (stiff movements)
resting
tremor
(pill rolling, looks like picking at clothes)
loss of writing reflexes
What is BradyKinesia?
Slowed
ability to
start
and
continue
movements.
Brady=slow Kines=movement
By age 70, how much has the dopamine in the substantia nigra decreased?
60-70%
Dopamine excess = ?
excess
movement
!
How can you treat dopamine excess?
Globus Pallidus Ablation
Deep Brain Stimulation:
Shuts off subthalamic nucleus of luys
Hemiballismus is always due to ________
stroke
What is the clinical feature of hemiballismus?
severe contralateral flinging movements
Which is more common, Parkison's or Hemiballismus?
Parkinsons
What is the age of onset for hemiballismus?
40 y/o
What are some behavioral changes for someone with Hemiballismus?
depression, mood swings
What are some abnormal movements of Hemiballismus?
Chorea-
involuntary
movements
Athetosis-
slow writhing
movements, confined to limbs
What is missing in huntington's disease
Caudate
--or else it can't receive dopamine, so it leads to too much dopamine
Hemiballismus is due to
stroke in the
subthalamic nucleus
and results in excess movements on the contralateral side
T/F: Huntington's disease is caused by autosomal dominant mutation
True
False
TRUE
What types of medicine can treat Parkinson's disease?
L-Dopa and Dopacrboxylase
Damage in the __________ causes hemiballismus
Subthalamic nucleus of luys
Author
carolinc
ID
83226
Card Set
14-Movement
Description
clinical conditions of movement
Updated
2011-05-04T03:54:23Z
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