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Pharm Final II, Psychotropics
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Basis for selection of psychotropic drugs (5):
Availability
General Behavioral Actions
Side Fx
Reported Therapeutic Fx
Neurochemistry
FDA approved psychotropics (3)
Clomipramine
Fluoxetine
Selegiline
Which FDA approved drugs are used to tx separation anxiety in dogs (2)? What do they act on?
Clomipramine (Serotonin & Norepi)
Fluoxetine (Serotonin)
What FDA Approved drug is used to treat canine cognitive dysfunction? What does it act on?
Selegiline, MOAf
What areas of the brain does serotonin act on & what are the effects (4)?
Limbic Areas- anxiety & panic
Basal Ganglia- compulsive disorder
Frontal Cortex- mood
Neurons of the brainstem- sleep
General effects of Serotonin (3):
Anti-Anxiety
Anti-compulsive
Behavioral calming effect
Fx & Side Fx of Acepromazine in...
Dogs (3):
Cats (2):
Dogs
:
Useful in some cases
Traquilizer
No anti-anxiety
Cats
:
Traquilizer
No anti-anxiety
Fx & Side Fx of Diazapam in...
Dogs: (2)
Cats: (2)
Dogs
:
Rapid Metab
May release inhibition
Cats
:
Sedation
Hepatic Necrosis
Fx & Side Fx of Busperone (Buspar) in...
Dogs (2):
Cats (2):
Dogs
:
Mild GIT Fx
Social Behavior Changes
Cats
:
Mild GIT Fx
Social Behavior Changes
Fx & Side Fx of Amitryptyline(Elavil) in...
Dogs (3):
Cats (2):
Dogs
:
Mild Sedation
GI Fx
Anti-Cholinesterase
Cats
:
Mild Sedation
Anti-Cholinesterase
Fx & Side Fx Paroxetine (Paxil) in...
Dogs(2):
Cats(2):
Dogs
:
Anti-cholinesterase
Restlessness
Cats
:
Anti-cholinesterase
Restlessness
Fx & Side Fx of Clomipramine (clomicalm) in...
Dogs(2):
Cats(2):
Dogs
:
Mild Sedation
Vomiting on an empty stomoch
Cats
:
Mild Sedation
Vomiting on an empty stomach
Fx & Side Fx of Fluoxetine (Prozac) in...
Dogs:
Cats (2):
Dogs
:
Cats
:
Anti-Choliesterase
Sleepiness
Phenothiazines :
Ace
Azasperones:
Burspirone (Buspar)
Tricyclic Antidepressants (2):
Amitriptyline (Elavil)
Clomipramine (Clomicalm)
SSRI (2):
Paroxetine (Paxil)
Fluoxetine (Prozac)
What Drugs can be used to Tx fear/phobias in dogs (3)?
Diazapam
Transene (Cloirazepate Dipotassium)
Alprazolam
What Drugs are used to Tx general anxiety in dogs (3)?
Azapirones
Loarzapam (geriatrics)
SSRI
What Drugs are used to Tx Seperation Anxiety in dogs (3)?
Diazapam
Clomipramine HCl (Clomicalm)
What Drugs are used to Tx Anxiety in cats (4)?
Azapirones
Clomipramine HCl (Clomicalm)
Diazepam
SSRI's
What drugs are used to Tx urine spraying in cats (4)?
Diazapam
Azapirones
SSRI
Clomipramine HCl (Clomicalm)
What durgs are used to Tx Compulsive Behaviors in dogs (2)?
SSRI's
Clomipramine HCl (Clomicalm, Tricyclic)
What drugs are used to Tx Sleep Disorders in dogs?
MOI's
What drugs are used to Tx Cognitive Dysfunction in dogs?
MOI's
What drugs are used to Tx depression in dogs and cats?
Fluoxetine (SSRI)
What drugs are used to Tx eating disorders in dogs and cats?
Fluoxetine (SSRI)
What drugs are used to Tx panic disorders in dogs and cats?
Fluoxetine (SSRI)
What drugs is used to Tx urine marking in Dogs and Cats?
Amitriptyline
What drugs are used to Tx hyperesthesia in cats?
Clomipramine HCl (Clomicalm, Tricyclic)
What drugs are used to Tx Acral Lick Dermititis in dogs
Clomipramine HCl (Clomicalm, Tricyclic)
What Drugs are used to Tx tail chasing/flank sucking in dogs?
Clomipramine HCl (Clomicalm, Tricyclic)
What drugs are used to Tx aggression?
SSRI
Tricyclic Antidepressants can be used with _(3)__ when single drug Tx's fail
Benxodiazapines
Buspirone
Trazadone
SSRI's can be used with _(2)__ when single drug Tx's fail
Buspirone
Trazadone
Benzodiazapines can be used with _(2)__ when single drug Tx's fail
MOI
TCA
Baseline psychotrpoic drugs (3):
(Benzodiazapines)
Alprazolam
Lorazepam
Chlorazepam
Atypical psychotropic Drugs (2):
Buspirone
Trazodone
What drug can cause mortalities d/t cardiac abnormalities?
Citalopram
What is the 1/2 life for Fluoxetine HCl (Prozac)?
4-16 days
MOI's should not be given with... (2)
SSRI's
TCA's
TCA's should not be given with... (3)
Cimetidine
Amitraz
Ketconazole
What should no be given with TCAs b/c it inhibits cytochrome P-450?
Cimetidine
What drugs can cause serotonin syndrome?
MOI's + Mitaban Dip, Preventic Collars, TCA or SSRI's
What drugs affect learning processes (necessary for behavior modificiation)?
Benzodiazapines
Phenothiozines
What drugs may facilitate learning?
TCA's
Author
HLW
ID
82915
Card Set
Pharm Final II, Psychotropics
Description
Pharm Final II, Psychotropics
Updated
2011-05-02T14:10:43Z
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