What makes fat- soluable Vita so unique?
- They require bile and other lipids to be absorbed in the small intestine.
- They get circulated away from small intestine in lymph via chylomicrons
- Large amt can be toxic.
- Can be destroyed light and heat, except D
Vita A and Carotenoids
- Carotenoids are Preformed compound (in animals)
- Retinol is the free floating form of Vita A
- Beta Caretene is a Provitamin A, also an antioxidant; mostly abundant in yellow and orange veggies and fruits.
- High intake of Vita A can lead to death. (not carotenoids)
Orange skin due to too much carotenoids, in food (veggies, carrots)
Deficiency of Vita A
Can lead to blindness, VADD, Xerophthamia - (damage of the cornea)
Vita D "sunshine" and "Prohormone"
- Produced by us, from the UV rays hitting the skin.
- Can also be found Fatty fish and some plants
- (1,25 - (OH-) D3 stimulates calcium absorption, w/o it, we wont able to take in calcium. Calcitriol Influence the absoption of Calcium.
- Toxicity is RARE, but can be dangerous
Rickets, Osteomalacia, and Osteoprosis
Hypercalcemia vs. Hypercalciuria
Deficiency of Vita D in Children, and Adults (soft and weak boned, vs. porous bones)
Deposit in tissue vs. kidney stone formation
Vita E - An Antioxidant
- Protects Cells membrane
- Activated form - Alpha-tocopherol, found in fatty foods - oil, seeds, nuts
- Protect from cataracts formation
Vita Deficiency & Toxicity - RARE
- But can lead to hemolytic anemia and Neuromuscular problems.
- Toxicity can lead to bleeding.
Vita K -"Blood clotter"
- Gets from dark green veggies, made in large intestines by microflora
- Involves with Calcium to clot blood, also in bone mineralizing
Vita K deficiency
- Can lead to weak bone and bleeding,
- Babies who were first born get Vita K injection.
- No UL.