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Which is the strongest statin?
Rosuvastatin (Crestor.)
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What's the brand name of Simvastatin?
Zocor.
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What's the brand name of Atorvastatin?
Lipitor.
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What's the brand name of Pravastatin?
Pravachol.
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What's the brand name of Lovastatin?
Mevacor, Altoprev.
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What's the brand name of Fluvastatin?
Lescol.
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Statins are best for lowering which lipid marker?
LDL (by 18-55%)
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Which class of drugs raises HDL the most (by 15-35%)?
Nictoinic acid.
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Which 2 classes are used to lower TG (by 20-50%)
Nicotinic acid and Fibric acids.
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Name 2 fibric acids.
Gemfibrozil, Fenofibrate
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What are the top 2 side effects of statins?
Myopathy, increased liver enzymes.
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What is a top side effect of bile acid sequestrants?
GI distress (nausea/constipation)
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What is a 3 side effects of nicotinic acid?
- Flushing, hyperglycemia, hyperuricemia
- (also hepatotoxicity)
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What is a 3 side effects of fibric acids?
Dyspepsia, gallstones, myopathy.
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Which 2 classes of lipid drugs have possible side effect of myopathy?
Statins, fibric acids.
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Which 2 classes of lipid drugs have possible side effect of hepatotoxicity?
Statins, nicotinic acids.
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Which class of lipid drugs have possible side effect of gallstones?
Fibric acids
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Which class of lipid drugs is contraindicated in severe gout?
Nicotinic acids
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What's the brand name of Gemfibrozil?
Lopid.
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Which class is Trilipix in? What's the generic name?
- Class: Fibric acids.
- Name: Fenofibric acid.
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Which 2 drugs does Vytorin combine?
Ezetimibe and simvastatin.
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What's the brand name of Ezetimibe?
Zetia.
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Which drug blocks absorption of cholesterol in the gut?
Ezetimibe (Zetia)
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Which drug combines a Cholesterol absorption inhibitor with a statin?
Vytorin.
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Which drug is a combo of Zetia/Zocor?
Vytorin.
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What is the brand name of Pitavastatin?
Livalo.
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What's the name for Welchol?
Colesevelam.
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What class of drug is Welchol?
Bile acid sequestrant.
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What are 3 bile acid sequestrants?
Cholestyramine, Colestipol, Colesevelam.
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Which is the only fibrate approved to be used with statins?
Trilipix.
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Name the top 3 strongest statins by generic name.
Rosuvastatin, Atorvastatin, Simvastatin
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Name the top 3 strongest statins by brand name.
Crestor, Lipitor, Zocor
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What time of day are statins usually taken? Why?
At night, because liver makes more cholesterol at night.
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Which statin is best taken with food?
Lovastatin (Mevacor)
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What is the cholesterol/HTN combo drug?
Caduet (amlodipine/atorvastatin).
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What's Simcor a combination of?
Niaspan and Simvastatin.
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