Adverse Effects of ARV

  1. Efavirenz
    • Teratogenic
    • Neuropsychiatric
    • Hyperlipidemia
  2. Nevaripine
    • Hepatotoxic
    • Women with CD4 >250
    • Men with CD4 > 400
    • Hyperlipidemia
  3. Etraverine
    Well tolerated
  4. Atazanavir
    • Hyperbilirubinemia
    • PR interval prolongation
    • Low nephrolithiasis
  5. Darunavir
    • High GI intolerance
    • Rash
  6. Darunavir
    • High GI intolerance
    • Rash
  7. Fosamprenavir
    • GI intolerance
    • Rash
  8. Indinavir
    • Nephrolithiasis
    • GI intolerance
  9. Lopinavir/ritonavir
    GI intolerance
  10. Nelfinavir
    Diarrhea
  11. Saquinavir
    GI intolerance
  12. Ritonavir
    • GI intolerance
    • Hepatitis
  13. Abacavir
    • Hypersensitivity reaction (once)
    • Rash
    • CV effects
  14. Didanosine
    • GI intolerance
    • Pancreatitis
    • Peripheral neuropathy
  15. Stavudine
    • Peripheral neuropathy
    • Pancreatitis
    • More lactic acidosis/hepatic steatosis and lipodystrophy
    • Hyperlipidemia
  16. Tenofovir
    • Headache
    • GI intolerance
    • Renal impairment
  17. Zidovudine
    • Headache
    • GI intolerance
    • Bone marrow suppression
  18. Emtricitabine
    Hyperpigmentation
  19. NNRTI
    • Rash (especially nevirapine)
    • DDI (inducers of CYP3A4)
  20. PI
    • Hyperlipidemia (not Atazanavir)
    • Insulin resistance and diabetes (not Atazanavir)
    • Lipodystrophy; lipoatrophy (not Atazanavir)
    • Elevated liver function tests
    • Increased bleeding risk in hemophiliacs
    • DDI (inhibit CYP3A4)
    • Osteonecrosis
  21. NNRTI
    • Lactic acidosis and hepatic steatosis (higher incidence with stavudine)
    • Lipodystrophy (higher incidence with stavudine)
  22. Enfuvirtide
    • Injection-site reactions
    • Hypersensitivity
    • Increased risk of bacterial pneumonia
  23. Maraviroc
    • Abdominal pain
    • URTI
    • Cough
    • Hepatotoxic
    • Musculoskeletal symptoms
    • Rash
    • Orthostatic hypotension
  24. Raltegravir
    • Nausea
    • Headache
    • Diarrhea
    • CPK elevation
Author
pdnguyen
ID
80842
Card Set
Adverse Effects of ARV
Description
Adverse Effects of ARV
Updated