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What are the 3 effects of infectious endocarditis?
- - Bacteria can initiate infectious endocarditis
- - And stimulate the immune system
- - The mature vegetation formed during the infection can detach from an infected heart valve and become an embolus that can then lodge in some distal organ.
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what are the 2 most common causes of infectious endocarditis?
Strep viridans and staph aureus
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What are the different types of plague?
- Sylvatic: seen in wild rodents and the primary reservoir of the organism
- Urban: see in cities, more infectious form because there are more potential hosts in the city than in the wild.
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Symptoms of tularemia: transmission through arthropod bite
- swollen lymph glands
- flu-like symptoms
- skin ulceration
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inhalation tularemia symptoms:
- respiratory disease
- swollen lymph nodes
- coughing
- pain under the breastbone
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What decides how tularemia will be present?
The inoculation site, the transmission,how far into the body the pathogen is spread
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Brucella is also known as?
Undulant fever b/c the pt in some cases dvelops a cycling pattern of symptoms called undulant fever
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How are CMV infections specifically diagnosed?
- CMV can be isolated from saliva, cervical secretions, seme, urine, and wbcs for years after the initial infection
- But difinitive diagnosis can be made by inclusion bodies
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How are arbovirus infections spread?
Mosquitos, sometimes mosquitos can pass the virus down a generation
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Chagas disease is also known as?
Trypanomsomiasis (sleeping sickness)
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What are the 2 life forms of the trypsonomas cruzi?
- Amistogotes: a large number created which cause the host cll to rupture
- Trypomastigote: Circle in blood to invade other host cells
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Plague
- Causitive agent: Yersinia pesits
- Mode of transmission: vector, bite of a rat flea (xenopsylla cheopis)
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Tularemia
- Causitive agent: Francisella tularnesis
- Transmission: Inhalation, tick-bite, ingestion of conta,minated meat or water, directly by contact with an abrasion or cut while skinning an infected animal
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Brucellosis
- Causitive agent: various bacteria of the genus brucella
- Transmission: by occupational contact or by ingesting contaminated animal products
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Lyme disease
- Causitive agent: the spirochete Borrelia Burgdorferi
- Transmission: through the Ixodes tick
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Mononucleusis
- Causitive agent: Human herpesvirus 4
- Transmission: Transmitted only after repeated contact with infected individuals
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Ebola/marburg
- Causitive agent: filoviruses
- Transmission: person to person
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Chagas
- Causitve agent: the parasite trypanosoma cruzi
- Transmission: vector, the reduvid, a larged winged insect that feeds on sleeping hosts
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Elephantitis
- Causitive agent: Wuchereria bancrofti and Brugia, both threadlike worms that lay coiled up in the lymphatic vessels of a human host for decades
- Transmission: Mosquito
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Endocarditis involves
- Colonization of the heart by bacteria
- Deposition of excessive amounts of platelets at the site
- Depositin of fibirn at the site
- Formatiion of mature vegetation
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Organisms of the genus Grancisella cause
Tularmia
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The most contagious form of plague is
The pneumonic form
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