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PCOL-Exam IV

  1. Levothyroxine
    Synthroid, Levoxyl, Levothroid, Unithroid

    T4

    Indicated for hypothyroidism

    • If doses are too high...
    • -increase in body temp
    • -palpitations
    • -tachycardia
    • -chest pain

    • Take on empty stomach
    • - 50% absorption

    Seperate from minerals/multivitamins
  2. Liothyronine
    Cytomel

    T3

    Indicated for hypothyroidism

    • If doses are too high...
    • -increase in body temp
    • -palpitations
    • -tachycardia
    • -chest pain

    • Take on empty stomach
    • - 50% absorption

    Seperate from minerals/multivitamins
  3. Liotrix
    Thyrolar

    T3 + T4

    Indicated for hypothyroidism

    • If doses are too high...
    • -increase in body temp
    • -palpitations
    • -tachycardia
    • -chest pain

    • Take on empty stomach
    • - 50% absorption

    Seperate from minerals/multivitamins
  4. Dessicated Thyroid
    Thyroid Hormone

    Indicated for hypothyroidism

    • If doses are too high...
    • -increase in body temp
    • -palpitations
    • -tachycardia
    • -chest pain

    • Take on empty stomach
    • - 50% absorption

    Seperate from minerals/multivitamins
  5. Methimazole
    Indicated for hyperthyroidism

    • MOA:
    • -Inhibits thioperoxidase enzyme thus decreasing thyroid hormone synthesis

    • ADR:
    • -Agranulocytosis (most concerning)
    • -Rash
    • -Joint aches
    • -Lower hepatic fxn
    • -Hair loss
  6. Propylthiouracil (PTU)
    Indicated for hyperthyroidism

    • MOA:
    • -Inhibits thioperoxidase enzyme thus decreasing thyroid hormone synthesis

    • ADR:
    • -Agranulocytosis (most concerning)
    • -Rash
    • -Joint aches
    • -Lower hepatic fxn
    • -Hair loss
  7. Thiocyanate
    Indicated for hyperthyroidism

    Inhibit sodium iodide symport

    • Causes aplastic anemia
    • (can be fatal)
  8. Percholorate
    Indicated for hyperthyroidism

    • Inhibits sodium iodide symport
    • Inhibits organification of iodide

    • Causes aplastic anemia
    • (Can be fatal)
  9. Iodide
    • Used as a paradoxical effect:
    • -For hyperthyroidism

    Reduces the thyroid gland fxn

    • ADR:
    • -Iodism: too much iodide
    • -Alterations in taste
    • -salivation
    • -Productive cough
  10. Lugol's Solution
    Antithyroid

    Thyroid hormone formation

    • Used as expectorant
    • -cause productive cough

    not used as much anymore

    • ADR:
    • -alterations in taste
    • -salivation
    • -productive cough (therapeutic use)
  11. SSKI
    Saturated solution of potassium iodide
    Antithyroid

    • Use:
    • -Thyroid hormone formation
    • -Expectorant
    • -Protection from 131I

    • Response decreases after a few days
    • -not for long term use
  12. 131I
    Radioactive Iodide

    Antithyroid

    DOC in hyperthyroidism tx

    • Destroys the cells in thyroid gland
    • -can lead to cancer

    Contraindicated in children and pregnant woman
  13. Compazine
    Prochlorperazine

    D2 receptor antagonists
  14. Tigan
    Trimethobenzamide

    D2 receptor antagonists
  15. Phenergan
    Promethazine

    D2 receptor antagonists
  16. Zofran
    Ondansetron

    5-HT3 receptor antagonists
  17. Kytril
    Granisetron

    5-HT3 receptor antagonists
  18. Anzemet
    Dolasetron

    5-HT3 receptor antagonists
  19. Aloxi
    Palonosetron

    5-HT3 receptor antagonists
  20. Reglan
    Metoclopramide

    D2 antagonist and 5-HT3 receptor antagonists
  21. Cisapride
    5-HT3 receptor antagonists & D2 antagonists

    Only used today in cats
  22. Emend
    aprepitant/fosaprepitant

    NK-1 receptor antagonist
  23. Marinol
    dronabinol

    CB-1 agonists
  24. Cesamet
    nabilone

    CB-1 antagonists
  25. alosetron
    Lotronex

    5-HT3 antagonist

    used for d-IBS
  26. lubiproston
    Amitiza

    used for c-IBS
  27. Cytotec
    Misoprostol

    • PGE2 receptor agonist
    • -stomach protectant
  28. Sucralfate
    Stomach protectant
  29. Tagamet
    Cimetidine

    H2 receptor antagonist
  30. Zantac
    Ranitidine

    H2 receptor antagonist
  31. Axid
    Nizatidine

    H2 receptor antagonist
  32. Pepcid
    Famotidine

    H2 receptor antagonist
  33. Prilosec/Zegerid
    Omeprazole

    PPIs
  34. Nexium
    Esomeprazole

    PPIs
  35. Prevacid
    Lansoprazole

    PPIs
  36. Kapidex
    Dexlansoprazole

    PPIs
  37. Aciphex
    Rabeprazole

    PPIs
  38. Protonix
    Pantoprazole

    PPIs
  39. Xolair
    Omalizumab

    Anti-IgE

    commonly used in asthma

    prevents the hypersensitivity rxn from starting
  40. Cromolyn
    Mast cell stabilizer

    commonly used in asthma
  41. Nedocromil
    Mast cell stabilizer

    commonly used in asthma
  42. Benadryl
    diphenhydramine

    First generation antihistamine
  43. Tavist
    clemastine

    First generation antihistamine
  44. Dramamine
    Dimenhydrinate

    First generation antihistamine

    M1 blockade in vestibular apparatus
  45. Chlor-Trimeton
    chlorpheniramine

    First generation antihistamine
  46. brompheniramine
    First generation antihistamine
  47. Atarax/Vistaril
    hydroxyzine

    First generation antihistamine
  48. cyclizine
    First generation antihistamine
  49. Antivert
    Meclizine

    First generation antihistamine

    anti-emetic
  50. promethazine
    Phenergan

    First generation antihistamine
  51. Periactin
    Cyproheptadine

    First generation antihistamine

    • Also a 5-HT receptor blocker
    • -used to treat 5-HT syndrome
  52. Doxepin
    TCA, H1, and M1 antagonist

    • Antihistamine
    • -often used as a topical cream for itching
Author
pcophung
ID
80725
Card Set
PCOL-Exam IV
Description
Drugs for exam IV (not including previous materials)
Updated

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