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cerebr/o
cerebrum (largest part of the brain)
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cerebell/o
cerebellum (little brain)
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mening/o, meningi/o
meninges (membrane)
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myel/o
spinal cord or bone marrow
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phob/o
exaggerated fear or sensitivity
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phren/o, psych/o, thym/o
mind
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somn/o, somn/i, hypn/o
sleep
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spondyl/o, vertebr/o
vertebra
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stere/o
three-dimensional or solid
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tax/o
order or coordination
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thalam/o
thalamus (a room)
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ventricul/o
ventricle (belly or pouch)
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-mania
condition of abnormal impulse toward
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-paresis
slight paralysis
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central nervous system (CNS)
brain and spinal cord
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brain
portion of the central nervous system contained within the cranium
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cerebrum
largest portion of the brain; divided into right and left halves, known as cerebral hemispheres, which are connected by a bridge of nerve fibers called the corpus callosum; lobes of the cerebrum are named after the skull bones they underlie
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frontal lobe
anterior section of each cerebral hemisphere; responsible for voluntary muscle movement and personality
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parietal lobe
portion posterior to the frontal lobe; responsible for sensations such as pain, temperature, and touch
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temporal lobe
portion that lies below the frontal lobe; responsible for hearing, taste, and smell
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occipital lobe
portion posterior to the parietal and temporal lobes; responsible for vision
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cerebral cortex
outer layer of the cerebrum consisting of gray matter; responsible for higher mental functions
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thalamus/ diencephalon
each of two gray matter nuclei deep within the brain; responsible for relaying sensory information of the cortex
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gyri
convulutions (mounds) of the cerebral hemispheres
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sulci
shallow grooves that separate gyri
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fissures
deep grooves in the brain
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cerebellum
portion of the brain located below the occipital lobes of the cerebrum; responsible for control and coordination of skeletal muscles
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brianstem
region of the brain that serves as a relay between the cerebrum, cerebellu, and spinal cord; responsible for breathing, heart rate, and body temperature; the three levels are the mesencephalon (midbrain), pons, and medulla oblongata
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ventricles
series of interconnected cavities within the cerebral hemispheres and brainstem filled with cerebrospinal fluid
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cerebrospinal fluid (CSF)
plasma-like clear fluid circulating in and around the brain and spinal cord
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spinal cord
column of nervous tissue from the brainstem through the vertebrae; responsible for nerve conduction to and from the brain and the body
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meninges
three membranes that cover the brain and spinal cord, consisting of the dura mater, pia mater, and arachnoid mater
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peripheral nervous system (PNS)
nerves that branch from the central nervous system including nerves of the brain (cranial nerves) and spinal cord (spinal nerves)
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cranial nerves
12 pairs of nerves arising from the brain
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spinal nerves
31 pairs of nerves arising from the spinal cord
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sensory nerves
nerves that conduct impulses from body parts and carry sensory information to the brain; also called afferent nerves
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motor nerves
nerves that conduct motor impulses form the brain to muscles and glands; also called efferent nerves
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autonomic nervous system (ANS)
nerves that carry involuntary impulses to smooth muscle, cardiac muscle, and various glands
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hypothalamus
control center for the autonomic nervous system located below the thalamus (diencephalon)
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sympathetic nervous system
division of the autonomic nervous system that is concerned primarily with preparing the body in stressful or emergency situations
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parasympathetic nervous system
division of the autonomic nervous system that is most active in ordinary conditions; it counterbalances the effects of the sympathetic system by restoring the body to the restful state after a stressful experience.
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aphasia/dysphasia
impairment b/c of localized brain injury that affects the understanding, retrieving, and formulating of meaningful and sequential elements of language, as demonstrated by an inability to use or comprehend words; occurs as a result of stroke, head trauma, or disease
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coma
a general term referring to levels of decreased consciousness with varying responsiveness, a common method of assessment is the Glasgwo Coma Scale
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delirium
a state of mental confusion caused by disturbances in cerebral function; the many causes include fever, shock, and drug overdose
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dementia
an impairment of intellectual function characterized by memory loss, disorientation, and confusion
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motor deficit
loss or impairment of muscle function
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sensory deficit
loss or impairment of sensation
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neuralgia
pain along the course of a nerve
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paralysis
temporary or permanent loss of motor control
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flaccid paralysis
defective (flabby) or absent muscle control caused by a nerve lesion
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spastic paralysis
stiff and awkward muscle control caused by a central nervous system disorder
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hemiparesis
partial paralysis of the right or left half of the body
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sciatica
pain that follows the pathway of the sciatic nerve, caused by compression or trauma of the nerve or its roots
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seizure
sudden, transient disturbances in brain function resulting from an abnormal firing of nerve impulses; may or may not be associated with convulsion
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convulsion
to pull together; type of seizure that causes a series of sudden involuntary contractions of muscles
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tactile stimulation
evoking a response by touching
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hyperesthesia
increased sensitivity to stimulation such as touch or pain
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paresthesia
abnormal sensation of numbness and tingling w/out objective cause
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agnosia
any of many types of loss of neurologic function involving interpretation of sensory information
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astereognosis
inability to judge the form of an object by touch
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atopognosis
inability to locate a sensation properly, such as an inability to locate a point touched on the body
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Alzheimer disease
disease of structural changes in the brain resulting in an irreversible deterioration that progresses from forgetfulness and disorientation to loss of all intellectual functions, total disability, and death
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amyotrophic lateral sclerosis (ALS)
condition of progressive deterioration of motor nerve cells resulting in total loss of voluntary muscle control; symptoms advance from muscle weakness in the arms and legs, to the muscles of speech, swallowing, and breathing, to total paralysis and death; also known as Lou Gehrig disease
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cerebral palsy (CP)
condition of motor dysfunction caused by damage to the cerebrum during development or injury at birth; characterized by partial paralysis and lack of muscle coordination
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cerebrovascular disease
disorder resulting from a change within one or more blood vessels of the brain
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cerebral arteriosclerosis
hardening of the arteries of the brain
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cerebral atherosclerosis
condition of lipid (fat) buildup within the blood vessels of the brain
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cerebral aneurysm
dilation of a blood vessel in the brain
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cerebral thrombosis
presence of a stationary clot in a blood vessel of the brain
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cerebral embolism
obstruction of a blood vessel in the brain by an embolus transported through the circulation
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cerebrovascular accident (CVA)/ stroke
damage to the brain caused by cerebrovascular disease, such as occlusion of a blood vessel by a thrombus or embolus (ischemic stroke) or intracranial hemorrhage after rupture of an aneurysm (hemorrhagic stroke)
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transient ischemic attack (TIA)
brief episode of loss of blood flow to the brain, usually caused by partial occlusion that results in temporary neruologic deficit (impairment); often precedes a CVA
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encephalitis
inflammation of the brain
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epilepsy
disorder affecting the central nervous system; characterized by recurrent seizures
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tonic-clonic seizure
stiffening-jerking; a major motor seizure involving all muscle groups; previously termed grand mal (big bad) seizure
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absence seizure
seizure involving a brief loss of consciousness w/out motor involvement; previously termed petit mal (little bad) seizure
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partial seizure
seizure involving only limited areas of the brain with localized symptoms
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glioma
tumor of glial cells graded according to degree of malignancy
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herniated disk or disc
protrustion of a degenerated or fragmented intervertebral disk so that the nucleus pulposus protrudes, causing compression on the nerve root
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herpes zoster
viral disease affecting the peripheral nerves, characterized by painful blisters that spread over the skin following the affected nerves, usually unilateral; also known as shingles
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Huntington chorea/ Huntington disease (HD)
hereditary disease fo the central nervous system characterized by bizarre, involuntary body movements and progressive dementia
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hydrocephalus
abnormal accumulation of cerebrospinal fluid in the ventricles of the brain as a result of developmental anomalies, infection, injury, or tumor
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meningioma
benign tumor of the coverings of the brain (the meninges)
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meningitis
inflammation of the meninges
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migraine headache
paroxysmal (sudden, periodic) attacks of mostly unillateral headache, often accompanied by disordered vision, nausea, or vomiting, lasting hours or days and caused by dilation of arteries
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multiple sclerosis (MS)
disease of the central nervous system characterized by the demyelination (deterioration of the myelin sheath) of nerve fibers, with episodes of neurologic dysfunction (exacerbation) followed by recovery (remission)
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myasthenia gravis
autoimmune disorder that affects the neuromuscular junction, causing a progressive decrease in muscle strength; activity resumes and strength returns after a period of rest
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myelitis
inflammation of the spinal cord
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narcolepsy
sleep disorder characterized by a sudden, uncontrollable need to sleep, attacks of paralysis (cataplexy), and dreams intruding while awake (hypnagogic hallucinations)
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neural tube defects
congenital deformities of the brain and spinal cord caused by incomplete development of the neural tube, the embryonic structure that forms the nervous system
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anencephaly
defect in closure of the cephalic portion of the neural tube that results in incomplete development of the brain and bones of the skull; the most drastic neural tube defect usually results in a stillbirth
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spina bifida
defect in development of the spinal column characterized by the absence of the vertebral arches, often resulting in pouching of the meninges (meningocele) or of the meninges and spinal cord (meningomyelocele); considered to be the most common neural tube defect.
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parkinson disease
condition of slowly progressive degeneration in an area of the brainstem (substantia nigra) resulting in a decrease of dopamine (a chemical neurotransmitter necessary for proper movement); characterized by tremor; rigidity of muscles, and slow movements (bradykinesia); usually occurs later in life
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hemiplegia
paralysis on one side of the body
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paraplegia
paralysis from the waist down
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quadriplegia
paralysis of all four limbs
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poliomyelitis
inflammation of the gray matter of the spinal cord caused by a virus, often resulting in spinal and muscle deformity and paralysis
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polyneuritis
inflammation involving two or more nerves, often caused by a nutritional deficiency, such as lack of thiamine
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sleep apnea
periods of breathing cessation (10 secs or more) that occur during sleep, often causing snoring
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electrodiagnostic procedures
diagnostic procedures used to evaluate the function of the nervous system by recording the electrical signals produced in the brain, spinal cord, and peripheral nerves.
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electroencephalogram (EEG)
record of the minute electrical impulses of the brain; used to identify neurologic conditions that affect brain function and level of consciousness
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evoked potentials
record of minute electrical potentials (waves) that are extracted from ongoing EEG activity to diagnose auditory, visual, and sensory pathway disorders; also used to monitor the neurologic function of patients during surgery.
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polysomnography (PSG)
recording of various aspects of sleep to diagnose sleep disorders
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lumbar puncture (LP)
introduction of a specialized needle into the spine in the lumbar region for diagnostic or therapeutic purposes, such as to obtain CSF for testing; also called spinal tap.
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magnetic resonance imaging(MRI)
nonionizing imaging technique using magnetic fields and radiofrequency waves to visualize anatomic structures (especially soft tissue), such as the tissues of the brain and spinal cord
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magnetic resonance angiography (MRA)
magnetic resonance imaging of blood vessels to detect pathologic conditions, such as thrombosis and atherosclerosis
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intracranial MRA
magnetic resonance image of the head to visualize the vessels of the circle of Willis (common site of cerebral aneurysm, stenosis, or occlusion)
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extracranial MRa
magnetic resonance image of the neck to visualize the carotid artery
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nuclear medicine imaging
radionuclide organ imaging
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single-photon emission computed tomography (SPECT) brain scan
scan combining nuclear medicine and computed tomography to produce images of the brain after the administration of radioactive isotopes
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positron-emission tomography (PET)
technique combining nuclear medicine and computed tomography to produce images of brain anatomy and corresponding physiology; used to study stroke, Alzheimer disease, epilepsy, metabolic brain disorders, chemistry of nerve transmissions in the brain, and so on; provides greater accuracy than SPECT, but is used less often b/c of cost and the limited availability of the radioisotopes.
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radiography
x-ray imaging
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cerebral angiogram
x-ray of blood vessels in the brain after intracarotid injection of contrast medium
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computed tomography (CT) of the head
computed tomographic images fo the head used to visualize abnormalities, such as brain tumors and malformations
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myelogram
x-ray of the spinal cord obtained after intraspinal injection of contrast medium
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reflex testing
test performed to observe the body's response to a stimulus
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deep tendon reflexes (DTR)
involuntary muscle contraction after percussion at a tendon indicating function; positive findings are either no reflex response or an exaggerated response to stimulus; numbers are often used to record responses
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Babinski sign
pathologic response to stimulation of the plantar surface of the foot; a positive sign is indicated when the toes dorsiflex (curl upward)
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transcranial Doppler sonogram
image made by sending ultrasound beams through the skull to assess blood flow in intracranial vessels; used in the diagnosis and management of stroke and head trauma
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carotid endarterectomy
incision of coring of the lining of the carotid artery to clear a blockage caused by the buildup of atherosclerotic plaque or a clot; an open procedure used to treat patients who are at risk for stroke
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craniectomy
excision of part of the skull to approach the brain
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craniotomy
incision into the skull to approach the brain
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diskectomy discectomy
removal of a herniated disk; often done percutaneously
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endovascular neurosurgery/ interventional neuroradiology
minimally invasive techniques for diagnosis and treatment of disorders within the blood vessels of the neck, brain, and spinal cord using specialized catheters inserted percutaneously into the femoral artery and guided by angiographic imaging to the treatment site; performed in a specialized angiographic laboratory by interventional neuroradiologists
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laminectomy/ vertebral lamina
- excision of one or more laminae of the vertebrae to approach the spinal cord.
- flattened posterior portion of the vertebral arch
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microsurgery
use of a microscope to dissect minute structures during surgery
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neuroplasty
surgical repair of a nerve
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spondylosyndesis
spinal fusion
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chemotherapy
treatment of malignancies, infections, and other diseases with chemical agents to destroy selected cells or impair their ability to reproduce
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radiation therapy
treatment of neoplastic disease using ionizing radiation to impede the proliferation of malignant cells
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stereotactic or stereotaxic radiosurgery
radiation treatment to inactive malignant lesions using multiple, precise external radiation beams focused on a target with the aid of stereotactic frame and imaging such as CT, MRI or angiography; used to treat inoperable brain tumors and other lesions
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stereotactic or stereotaxic frame
mechanical device used to localize a point in space, targeting a precise site
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analgesic
agent that relieves pain
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anticonvulsant
agent that prevents or lessens convulsion
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hypnotic
agent that induces sleep
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affect
emotional feeling or mood
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flat affect
significantly dulled emotional tone or outward reaction
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apathy
a lack of interest or display of emotion
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catatonia
a state of unresponsiveness to one's outside environment, usually including muscle rigidity, staring, and inability to communicate
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delusion
a persistent belief that has no basis in reality
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grandiose delusion
a person's false belief that he or she possesses great wealth, intelligence, or power
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persecutory delusion
a person's false belief that someone is plotting against him or her with the intent to harm
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dysphoria
a restless, dissatisfied mood
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euphoria
an exaggerated, unfounded feeling of well-being
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hallucination
a false perception of the senses for which there is no reality; most commonly hearing or seeing things
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ideation
the formation of thoughts or ideas, such as suicidal ideation
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mania
state of abnormal elation and increased activity
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neurosis
a psychologic condition in which anxiety is prominent
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psychosis
a mental condition characterized by distortion of reality resulting in the inability to communicated or function within one's environment
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thought disorder
thougth that lacks clear processing of logical direction.
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major depression, major depressive illness, clinical depression, major affective disorder, unipolar disorder
a disorder causing periodic disturbances in mood that affect concentration, sleep, activity, appetite, and social behavior; characterized by feelings of worthlessnes,s fatigue, and loss of interest
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dysthymia
a milder affective disorder characterized by chronic depression
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manic depression, bipolar disorder (BD)
an affective disorder characterized by a mood swings of mania and depression (extreme up and down states)
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seasonal affective disorder(SAD)
an affective disorder marked by episodes of depression that most often occur during the fall and winter and that remit in the spring
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dyslexia
a developmental disability characterized by difficulty understanding written or spoken words, sentences, or paragraphs that affects reading, spelling, and self-expression
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attention-deficit/hyperactivity disorder (ADHD)
a dysfunction characterized by consistent hyperactivity, distractibility, and lack of control over impulses, which interferes with ability to function normally at school, home, or work
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mental retardation
a condition of subaverage intelligence characterized by an IQ of 70 or less, resulting in the inability to adapt to normal social activities
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anorexia nervosa
a severe disturbance in eating behavior caused by abnormal perceptions about one's body weight, as evidenced by an overwhelming fear of becoming fat that results in a refusal to eat and body weight well below normal
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bulimia nervosa
an eating disorder characterized by binge eating followed by efforts to limit digestion though induced vomiting, use of laxitives, or excessive exercise
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substance abuse disorders
mental disorders resulting from abuse of substances such as drugs, alcohol, or other toxins, causing personal and social dysfunction; identified by the abused substance, such as alcohol abuse, amphetamine abuse, opioid (narcotic) abuse, and polysubstance abuse.
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schizophrenia
a disease of brain chemistry causing a distorted cognitive and emotional perception of one's environment; symptoms include disortions of normal function (such as disorgazied thought, delusions, hallucinations, and catatonic behavior), flat affect, apathy, and withdrawal from reality
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electroconvulsive therapy (ECT)
electrical shock applied to the brain to induce convulsions; used to treat patients with severe depression
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light therapy
use of specialized illuminating light boxes and visors to treat seasonal affective disorder
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psychotherapy
treatment of psychiatric disorders using verbal and nonverbal interaction with patients, individually or in a group, employing specific actions and techniques
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behavioral therapy
treatment to decrease or stop unwanted behavior
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cognitive therapy
treatment to change unwanted patterns of thinking
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psychotropic drugs
medications used to treat mental illnesses
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antianxiety agents/ anxiolytic agents
drugs used to reduce anxiety
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antidepressant
agent that counteracts depression
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neuroleptic agents
drugs used to treat psychosis, especially schizophrenia
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sedative
agent that has a calming effect of quiets nervousness
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ALS
amyotrophic lateral sclerosis
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ADHD
attention-deficit/hyperactivity disorder
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ANS
autonomic nervous system
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CNS
central nervous system
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CVA
cerebrovascular accident
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ECT
electroconvulsive therapy
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GAD
generalized anxiety disorder
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MRA
magnetic resonance anngiography
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MRI
magnetic resonance imaging
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NCV
nerve conduction velocity
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OCD
obsessive-compulsive disorder
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PET
positron-emission tomography
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PNS
peripheral nervous system
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PTSD
posttraumatic stress disorder
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SAD
seasonal affective disorder
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SPECT
single-photon emission computed tomography
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TIA
transient ischemic attack
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generalized anxiety disorder (GAD)
the most common anxiety disorder; characterized by chronic , excessive, uncontrollable worry about everyday problems, affects the ability to relax or concentrate, but does not usually interfere with social interactions or employment; physical symptoms include muscle tension, trembling, twitching, fatigue, headaches, nausea, and insomnia
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panic disorder
a disorder of sudden, recurrent attacks of intense feelings, including physical symptoms that mimic a heart attack with a general sense of loss of control or feeling that death is imminent; often progresses to agoraphobia
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phobia
exaggerated fear of a specific object or circumstance that causes anxiety an dpanic; named for the object or circumstance, such as agoraphobia, claustrophobia, and acrophobia
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posttraumatic stress disorder (PTSD)
a condition resulting from an extremely traumatic experience, injury, or illness that leaves the sufferere with persistent thoughts and memories or the ordeal; symptoms include feelings of fear, detachment, exaggerated startle response, restlessness, nightmares, and avoidance of anything or anyone who triggers the painful recollections
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obsessive-compulsive disorder (OCD)
an anxiety disorder featuring unwanted, senseless obsessions accompanied by repeated compulsions; can interfere with all aspects of a person's daily life
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hypochondriasis
a preoccupation with thoughts of disease and concern that one is suffering from a serious condition of persists despite medical reassurance to the contrary
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autism
a develpomental disability, commonly appearing during the fist three years of life, resulting from a neurologic disorder affecting brain function, as evidenced by difficulties with verbal and nonverbal communication and an inability to relate to anything beyond oneself in social interactions
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