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Name the reactant and product, and any co factors: aconitase?
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Name the reactant and product, and any cofactors for isocitrate dehydrogenase?
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Name the reactant product and any cofactos for alpha-ketoglutarate dehydrogenase.
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Show the step in TCA cycle of substrate-level phosphorylation.
- Nucleotide diphosphate kinase leads to ATP production from GTP.
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Name the products, reactants, and cofactors involved in succinate dehydrogenase.
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You hydrate furmate to form what molecule?
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Name the products, reactants, and cofactors for enzyme malate dehydrogenase.
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What is the main regulating enzyme for the TCA cycle?
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What happens to PDH in a state of starvation?
PDH Kinase increases, which deactivates PDH. This shuts down gylcolysis and prevents oxidation of pyruvate to CO2.
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In what cell types are PDH Kinase activated?
Activated in tumor cells.
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In what type of cells are PDH Phosphatase activated
- Activated in insulin cells in liver adipose.
- Inactivated by NADH.
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Isocitrate dehydrogenase and alpha-ketoglutarate dehydrogenase are inhibited by what?
- Inhibited by increase in ATP and increase in NADH.
- This means that there is an increase in citrate, which inhibits PFK (shuts off gylcolysis).
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What are the reactions that replenish OAA?
- pyruvate carboxylase
- PEPCKase (cofactor GDP and CO2 added)
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What is the reaction that replenishes malate?
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What is oxidative phosporylation?
- It is the syntheiss of ATP powered by re-oxidation of NADH or FADH2.
- Major source of ATP synthesis.
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Where does oxidative phosphorylation take place?
In the mitochondria matrix and inner mitochondria membrane.
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What are the two phases of oxidative phosphorylation?
- Oxidative phase: refers to NADH and FADH2 oxidized to H2O.
- Phosphorylation phase: refers to ATP synthesis
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What is redox potiental mean?
Is the measure of how strongly compound wants an electron.
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Define what an oxidizing agent and reducing agent is.
- Oxidizing agent: accept electrons and are reduced in a redox reaction.
- Reducing agent: donates electrons and is oxidized in a redox reaction.
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The tendency for a reactant to be oxidized or reduced is found through its reducation potiental E. Write the equation that shows the relation of delta G and delta E to show the spontaneous direction of a reaction.
deltaG^o= -nF(deltaE^o)
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What is Faraday's constant value?
96,500 J/Vxmol
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