-
category of drugs used to treat elevated blood pressure
antihypertensives
-
act to block beta 1 receptors and lowers vascular resistance
beta blockers
-
stimulate or block alpha receptors and decrease BP
adrenergic blockers
-
act by relaxing smooth muscles of the blood vessels
direct acting vasodilators
-
inhibit formation of angiotensin II to lower peripheral resistance
ACE inhibitors
-
act to block angiotension at receptor sites
angiotension II receptor antagonists
-
act by decreasing cardiac contractility and relaxing coronary arteries
calcium channel blockers
-
major s/e of antihypertensives
hypotension, edema, impotence
-
s/e of antihypertensive: minoxidil
hair growth
-
category of drugs used to treat fluid retention and hypertension
diuretic
-
acts on distal tubules to excrete Na, K, and water
thiazide diuretics
-
act on loop of Henle to inhibit transport of Na
loop diuretics
-
increase the osmolality in the renal tubules
osmotic diuretics
-
block the action of carbonic anhydrase to cause excretion of Na, K, and HCO3
carbonic anhydrase inhibitors
-
act on the distal collecting tubles to interfere with the Na-K pump
potassium sparing diuretics
-
s/e of potassiom sparing diuretics
hyperkalemia
-
s/e of thiazide, loop, and osmotic diuretics
hypokalemia
|
|