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ID 2, Exam 2
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Ansa Macrolides: Overview
natural or semi-synthetic
belong to
ansamycin group
of antibiotics
these possess an aromatic ring system spanned by an
alaphatic chain/bridge
History
Semisynthetic derivative of
rifamycin B
first used clinically in 1968
Rifampin
= USAN (United States Adopted Name)
Rifampicin
= INN (International Non-proprietary Name)
Source; Rifamycin B
Amycolatopsis mediterranei
is the source of the rifamycin complex -- Rifamycin A-E
Rifampin is a semi-synthetic derivative of rifamycin B
Rifamycin B
is preferentially produced by the organism upon addition of
sodium diethylbarbiturate
to the fermentation medium
Author
mwbora
ID
8012
Card Set
ID 2, Exam 2
Description
Rifampin
Updated
2010-02-24T23:48:08Z
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