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SFOS 15
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Index of contractility
dP/dt during isovolumentric contraction
measure of contractility
What provides most energy for cardiac function?
Secondary sources?
Oxidative metabolism of fatty acids
secondary - lactate and glucose
Volume work vs. Pressure work
Volume work - greater stroke volume (less energy), seen during exercise
Pressure work - greater developed tension (more energy), seen in hypertension
Phases of volume-pressure diagram
I - filling of ventricle
II - isovolumetric contraction
III - ejection from ventricle
IV - isovolumetric relaxation
Intrinsic cardiac regulation
Response to changes in venous return by inherent muscle properties
Frank-Starling mechanism
: greater contraction with more optimal filling stretch
Extrinsic cardiac regulation
Autonomic nervous system
Hormonal signaling
Effects of sympathetic stimulation
Increase SA node rate
Increases rate of conduction
Increases force of contraction
Effects of parasympathetic stimulation
Decreases SA node rate
Hyperpolarizes fibers between SA and AV nodes
Decreases force of contraction
Intrinsic heart rate
Heart rate prevailing during complete autonomic blockade
Author
zf2010
ID
80026
Card Set
SFOS 15
Description
SFOS 15
Updated
2011-04-16T20:04:12Z
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