Rocuronium Bromide (Zemuron)

Non-depolarizing neuromuscular blocker

Non-depolarizing neuromuscular blocker with a raped intermediate onset and duration of action.

Binding competitively to cholinergic receptors at the motor end plate to antagonize the action of acetylchoine. Effects reversible in presence of acetylcholinesterase inhibitors.

• Onset: 30-60 sec
• Peak: 1-3 min
• Duration: 30-60 min
• Half-Life: 14-18 min

Induction of skeletal muscle paralysis for RSI and/or ET intubation

Hypersensitivity to drug

Elevated HR, Elevated BP, should be administered with in adjusted doses under experienced clinicians.

Brochospasm

• RSI Dose: 600 ug/kg (.6mg/kg)
• Maintenance Dose: 100-200 ug (.1-.2mg/kg continuous infusion.

• RSI Dose: 600ug/kg (.6mg/kg)
• Maintenance Dose: 75-125ug/kg (.1-.2 mg/kg) continuous infusion.

As needed to maintain paralysis

IV/IO

Vials