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Precautions of Gliclazide/glimepramide?
- Ketoacidosis
- Type 1 Diabetes
- Renal impairment
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Adverse Effects of gliclazide/glimeparide??
- Hypoglycaemia
- weight gain
- Nausea, diarrhoea, metallic taste
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Dose of gliclazide?
- 40-320mg once or twice daily
- Start with 20mg once daily if 12-18y
- Controlled release: 30mg once daily initially
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Counselling of Gliclazide/Glimepramide??
- Take with food to minimise risk of hypos
- Avoid binge drinking since it can lower blood glucose level. Eat when you drink also.
- Make sure you and family members know how to treat hypos
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Dose of glimepramide?
- 1mg once daily initially
- increase by 1mg every 1-2 weeks, max 4mg daily
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